IPI-145, an oral, potent PI3K-delta inhibitor... - CLL Support

CLL Support

22,469 members38,605 posts

IPI-145, an oral, potent PI3K-delta inhibitor...

Cllcanada profile image
CllcanadaTop Poster CURE Hero
1 Reply

IPI-145, an oral, potent PI3K-d,? inhibitor, appears to be well tolerated and has shown initial clinical activity in pts with iNHL, MCL, and CLL.

Infinity released positive phase 1 data on IPI-145, its oral PI3K-inhibitor aimed at treating hematological malignancies.

The results demonstrated that IPI-145 showed clinical activity in B-cell and T-cell malignancies.

Source Abstract from ASH

ash.confex.com/ash/2012/web...

Written by
Cllcanada profile image
Cllcanada
Top Poster CURE Hero
To view profiles and participate in discussions please or .
Read more about...
1 Reply
jangreen profile image
jangreen

Hi this may be the breakthrough we all hope for only time will tell

You may also like...

Alterations of the immune system caused by CLL B‐cells

small molecular inhibitors (i.e, BTK inhibitors, PI3K inhibitors, BCL‐2 inhibitors) and T‐cell...

ASH 2019 CLL highlights and 'hot' topics - Drs Nicole Lamanna & Florence Cymbalista

Lamanna - ASH 2019 - Maturing CLL clinical trial data Dr. Nicole Lamanna, Associate Clinical...

CALQUENCE gets FDA approval for treating CLL

inhibiting its activity. In B-cells, BTK signaling results in activation of pathways necessary for...

ASH 2019: A Clinical Trial of Cannabis As Targeted Therapy for Indolent Leukemic Lymphoma

reduces lymphoma cell numbers in peripheral blood. There was no evidence of activation of caspase...

How Ibrutinib works over time

Hi, At ASH 2016 in San Diego, CA, I had the honor of once again interviewing Dr. Wiestner from the...