Tisomy 12

[venk_46]

Dx 203 CLL in Feb 2013,male, living in India, watch and wait till last week. I am Ighv mutated and no Zap 70 and CD 38.

My Fish test revealed no genetic deletion

Like 17p, 13q, 11q.

Due to gradual fall of Hb to 8 and lymphocytes around 100k, I was advised

B R chemo immunotherapy and stated on November 14.

My Fish test revealed that I have Trisimy 12..Any inputs on this Trisimy and how the prognosis, problems and experience may please be shared

[rcknow]

I have the same genetic type as you and had FCR therapy which finished about a year and a half ago. It went well. From all that I've read, trisomy 12 mutated responds well to chemotherapy and some people have had 15+ years of remission. Best wishes to you!

[venk_46 in reply to rcknow]

Thanks a lot . I feel greatly relieved after seeing your reply.

I just started Ist cycle of B - R.

I was given Bendamustin on 2 days at slow rate. My doctor wants to wait for couple of days for giving Rituximab infusion to get the benefit of reduced decease load .

Thanks again for promptness in replying

[Name-1]

I have Trisomy 12.But ,my experience is not typical.I had Th. R+Chl after one years with PR.

[SZUR]

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