I had check up with oncologist this week. Last January she told me that chemo would be sooner than later. I was able to avoid it all year. I have had CLL for 10 years. My WBC reached 193k. Last January I was at 150. Seems to be accelerating over the past 2 years. I have some swollen nodes. No other symptoms. Have lots of energy. I planned on going for second opinion at some point. Dr. suggested I go for second opinion before I could get the words out. That was a relief. She suggested I go to Moffitt Center in Tampa, FL which is about 3 hrs. from me. I asked her why I wasn't going to try ibrutinib etc. She said I didn't have the mutation. Not sure what that meant. Can anyone explain that? Will meet with her in January and then get information to make appt at the Center. She said they will repeat some tests, blood, possible Petscan and then might take bone marrow sample (had that done with no issues 10 years ago for diagnosis). She said the chemo would be 6 months...the usual effects like losing hair. Feeling blessed I have not needed treatment for so long but now feeling anxious. I will have a lot of questions answered at the Center but also wondered if anyone went thru chemo can tell me if we get rid of CLL by going thru it. Can it return after chemo? Have you ever heard of fractional chemo- gentler type of chemo?