I am please to announce that after my 9th cycle on the Imbruvica plus Venetoclax trial I am Min Residual Disease (MRD) Negative in the blood and Compete Response CR on the MRI. I hope it continues... I am very pleased given I am 17P deleted. My nodes were very big when I started. I was only on WW for 1 year before starting treatment due to node size.
I feel good. I have continue to work and exercise through the entire treatment. Side effects have not been too bad. I have been neutropenic a couple time but they just give me a shot and my ANC comes back up nicely.
I have had an outer ear infection and a toe infection and both were cured with topically antibiotics. My nails are not as strong as they use to be so I now take Biotin and it seems to help.
I will do another test to check for CLL Cells in my blood in 6 weeks. If they do not see CLL again then I will have a Bone Marrow Biopsy at the end of the year ( fun...)
If I am then MRD Negative I will be randomized and either stay of Imbruvica only a placebo. If I am not MRD negative then I will be either on Imbruvica only or both drugs.
Read more about how I got to this trial here:
Also, Happy New year to my Jewish CLL friends as well. There are many of us... Unfortunately