I have been on Ibrutinib for 3 years and most of that time my skin has been unbareably itchy . I was on two previous infusion trials which didn't work but this one is good with Lymphosites down to 9 from hundreds. I have occasional join pains mainly shoulders but they only last for 2 or3 days. The itching started with the first infusion some 5 years ago and is worse after swimming in the local pool but not always. Does anybody else have the same problems. I have tried various creams from GP and elsewhere but nothing seems to help sometimes.