Abbvie agrees to by Pharmacyclics

AbbVie Makes Cancer Therapy Push With a $21 Billion Deal

by Drew Armstrong

10:58 PM EST March 4, 2015

AbbVie Inc.

Since splitting off from parent Abbott Laboratories in 2013, AbbVie hasn’t completed one of the megadeals that have tempted much of the rest of the drug industry. Photographer: Kristoffer Tripplaar/Sipa USA/Getty Images

(Bloomberg) -- AbbVie Inc. agreed to buy Pharmacyclics Inc. in a $21 billion deal after beating out Johnson & Johnson for control of a blockbuster blood cancer therapy that will help it expand in the lucrative area of oncology.

Under the terms of the transaction, AbbVie will pay $261.25 per share comprised of a mix of cash and AbbVie equity, the two companies said in a statement today. The price is 39 percent higher than Pharmacyclics’s closing price on Feb. 24, the day before Bloomberg News reported that the company was considering a deal.

The purchase would help AbbVie reduce its reliance on Humira, its best-selling rheumatoid arthritis treatment while expanding into cancer therapy, one of the most promising areas of drug development. It would gain control of Imbruvica, an easy-to-use pill that costs about $100,000 a year, avoids certain serious side effects of chemotherapy, and is already approved for four different blood cancer uses.

Pharmacyclics was nearing an agreement to be acquired by Johnson & Johnson, which was discussing a price of about $250 per share, before AbbVie topped the offer at the last minute, a person with knowledge of the matter said. The person asked not to be identified as the details are private. Amy Jo Meyer, a J&J spokeswoman, declined to comment.

Rising Profits

Pharmacyclics had net income last year of $86 million, according to data compiled by Bloomberg. However, sales of Imbruvica are expected to grow to $3.56 billion in 2018 from $492 million last year, according to an average of estimates by analysts surveyed by Bloomberg, as it’s used in more types of cancer.

While Imbruvica will overlap with one of AbbVie’s top pipeline products, ABT-199 there should be room for both, said Asthika Goonewardene, an analyst with Bloomberg Intelligence. It may take until 2016 for ABT-199 to be approved, and while Imbruvica has shown itself to be a preferred drug for many patients, others may benefit from a different therapy. “Given all this, having two dogs in the race may not be a bad thing,” Goonewardene said in an e-mail.

AbbVie said it expects about 58 percent of the deal to be paid in cash, and 42 percent in stock, and to close mid-year. Its shares closed 1.1 percent higher at $60.27 in New York. Since splitting off from parent Abbott Laboratories in 2013, AbbVie hasn’t completed one of the megadeals that have tempted much of the rest of the drug industry.

It has tried, though. AbbVie and Shire Plc in October agreed to terminate a planned $52 billion acquisition by AbbVie that would have redomiciled the drugmaker abroad and given it a lower tax rate. AbbVie pulled its support for the transaction after proposed changes to U.S. rules.

Forecasts

In January, AbbVie gave a forecast for adjusted 2015 earnings near the low end of analysts’ estimates as competition from generic drugs eats into profits. Pharmacyclics shareholders will get to choose whether to take cash, stock or a combination.

Pharmacyclics is partnered with J&J on Imbruvica. The drug could eventually be used in solid tumors, and Pharmacyclics also has a partnership with AstraZeneca Plc to develop the drug for use with a new type of oncology treatment that triggers the body’s immune system to attack tumors.

“We’re looking forward to continuing our collaboration with the team at AbbVie to further develop and commercialize this important therapy,” J&J said in an e-mailed statement referring to Imbruvica.

Acquisitions by pharmaceutical and biotechnology companies reached a record $239 billion last year, according to data compiled by Bloomberg, as buyers from Actavis Plc to Bayer AG picked up new assets.

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7 Replies

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  • Thanks for posting this Jeff.

    Here's the link to the Bloomberg article:

    bloomberg.com/news/articles...

  • Neil,

    You are awesome. I couldn't get my link to work.

    Jeff

  • usatoday.com/story/money/bu...

    ABBVIE (the owner of ABT-199) just beat J&J and purchased Pharmacyclics for $21 Billion, ( Phamacyclics' one approved drug is Imbruvica/Ibrutinib). The CEO owns about 20% of the shares, which will translate into over $5 Billion, and he has about 620 employees that will become millionaires

  • Nice for some!

    I presume this makes no difference to those of us using Ibrutinib under an agreement with pharmacyclics? I am on a clinical trial under which the drug is provided by the company free to the NHS in England. There is a guarantee that patients on the trial can continue to receive Ibrutinib until progression or something better comes along.

  • I wonder how this will effect Janssen's co-development and joint marketing of ibrutinib?

  • Good question but as long as money is to be made there will be strange bedfellows, I'm sure. 😉

    Jeff

  • Good news to see that apt199will be approved next year I've been trial ing it now nearly twelve months no side affects brilliantly drug saved my life I'm back at work and leading a normall life

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