CLL Support Association
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Waldenstroms now Richter's Transformation

My husband was diagnosed with Waldenstroms a couple of years ago, and had check-ups every 6 months. Last November, he was diagnosed with Prostate Cancer, and completed 39 successful Proton Beam Treatments on March 20th. On April 9th, he continued to have night sweats, weakness, etc., and after two trips to the E.R., he finally was admitted on our third visit. At first they thought it might be meningitis, and a lumbar puncture was done. The results were negative. Then, his breathing became labored, and he was put on a ventilator, and later a kidney machine, and finally tube feeding. Before his organs completely shut down, the Oncologist came to me and said that I needed to do something before it was too late to do anything, and I gave my permission to begin the 96 hour Chemo Therapy. After this intense and aggressive chemo was completed, his organs started to return to normal, and he was taken off the ventilator, and later the kidney machine. He was suppose to have another 96 hour chemo session this Friday, but they are putting it off a week, waiting for an increase in his platelets and white blood cells. We have been in the CCU for almost a month, and the oncologist said that if he can survive the 6 Chemo sessions, he will be cancer free.

Has anyone else had these 96 hour chemo treatments?

3 Replies

I'm very sorry to hear about your husband's situation...

I had a Richter's transformation from CLL 8 months ago, and was treated with RCHOP in 6 cycles of 24 days. So far, so good.

I'm interested in knowing more about what type chemo is being used for 96 hours...




My husband is being treated by an Hemotolgist/Oncologist at the Mayo Clinic, and I'm almost certain that they mentioned DA-EPOCH-R. Having just been diagnosed a couple of weeks ago, we are new to all of this, and trying to learn as much as we can about this disease and treatment.

Thank you Chris



Thanks Kathleen...that is what I thought.

Here is a paper about the treatment if you are interested... bloodjournal.hematologylibr...

I couldn't tolerate the doxorubicin or vincristine after 4 rounds so the dropped those in favour of etoposide




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