Update on failing Calquence - Pirtobrutinib is Next

[ReneeSusan]

I spoke with my specialist from Upenn today and she wants to switch me to pirtobrutinib once it receives FDA approval for CLL in a few weeks.

My questions are for those in clinical trials for pirtobrutinib. Any feedback is much appreciated as this will be my 5th treatment regimen and I’m a little anxious.

How did they start the dosing, ramp up or full dose to start and where, at home or hospital? Side effects you experienced initially and long term, especially gastrointestinal side effects? Has it made a positive difference in your nodes and blood counts compared to your prior treatment? Did you have hair loss, wright gain or loss?

Hoping this will be the drug that will give me (us) a long durable remission.

Thank you.

Renee

[HopeME]

Hi Renee: I’m sorry you are facing the need for a new treatment. I don’t have any experience with pirtobrutinib but from what I’ve read here, it is a newer option with positive results. I’m sure you’ll get some feedback soon from those who have been prescribed this drug.

Have a nice day,

Mark

[ReneeSusan in reply to HopeME]

Thanks Mark. While I am a little apprehensive about starting another treatment, I’m also incredibly grateful and happy that their ARE new treatments available to us to extend our journey.

Renee

[Hidden]

You will receive more responses on the "CLL support" forum. This is the CLL America Support" forum which has next to no participation.

You should also lock your posts if you want responses.

Good luck!

[ReneeSusan in reply to Hidden]

Thanks, just did!

[Gradyboy]

Have you tried Venclexta yet?