as previously mentioned, I am intolerant of statins - simvastatin. The symptoms seem to creep up on me and build over a period of time. I have been on 10mg for 6 months - but the lethargy and tiredness and general feeling of brain fuzz is now intolerable. I wanted to ask if anyone has tried a 6 months off and 6 months on strategy. Would this be better than nothing or would it be harmful? My doctor is losing patience with me saying that I risk a stroke in the years to come if I don't follow advice. However, living with feeling so low is not how I want to be - whatever life I've got left! My cholesterol was 7.5 before I startyed taking the low dose - went down to 5.3. But I have a family history of heart disease!!