Cholesterol combats infection, why wou... - Cholesterol Support

Cholesterol Support
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Cholesterol combats infection, why would you want to lower it?

Concerned
Concerned
19 Replies

High cholesterol may be an indication that you've got a high level of inflammation for instance, that needs coping with.

Low cholesterol levels are linked to cancer.

19 Replies
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Mike262

This seems to be a Statement rather than a question and is more likely to confuse and startle people!

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DakCB-UK
DakCB-UK
in reply to Mike262

Yeah, it's out of context, unsubstantiated, confused (for example, the main question suggests cholesterol is preventative, the text beneath suggests it's restorative) and the answer is bleeding obvious: you'd want to lower cholesterol levels if they are not in response to an infection (or is it an inflammation? They're not the same thing: more confusion!) and the lipid hypothesis is correct... and as you can see from posting history, comrade Concerned appears to be a committed hypothesis denier, so that's what this is really about.

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Withattitude

I think being judgemental and critical is a really unhelpful response in any forum.

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DakCB-UK

So what would you have us do? Say nothing and not worry about fellow patients who may believe unsupported claims in this forum?

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Withattitude

Not at all. It is possible to say what you think without being critical and judgemental. There are many different beliefs out there regarding the medical impact of cholesterol and they don't all support the opinion that all cholesterol is bad. I also think that challenge makes us all take stock and re-evaluate our own position. As for the impact on fellow patients I think that is for fellow patients to decide not me or you.

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DakCB-UK

There are many different beliefs out there regarding lots of things and many of those are crazy too.

Bottom line is that it doesn't matter what I think because the site guidelines say "you are asked to provide references and links wherever relevant and possible" and this question did not. I'm disappointed that the moderators leave such rumours on this site unchallenged.

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Aliwally

Actually it's quite interesting because I was reading about rheumatoid arthritis and lipid levels. Last summer I was getting a lot of pain and stiffness in my fingers which I put down to the atorvastatin.

They have been about 70% better since I stopped taking it, but my research tells me that lipid levels can be disrupted maybe up to 10 years before symptoms of RA appear and RA is classically inflammatory.

Of course this could also be hypochondria instead of mild RA , I'm good at diagnosing myself and I'm not always right.

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MikePollard

Apparently low rates of cholesterol in old people is associated with higher death rates. This is pretty well supported.

eg:

weeksmd.com/2009/11/low-cho...

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zphelps

two words ...heart disease = death

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Concerned
Concerned
in reply to zphelps

Heart disease being due to stress (inflammation), smoking, and elevated blood sugar/insulin.

Cholesterol attempts to repair the damage?

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zphelps
zphelps
in reply to Concerned

clogs the artries, requires stints, by pass surgery results in cost to NHS tax payers, and eventually your family for the cost of funeral....

stress? if that was true i'd be dead now!!

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Concerned
Concerned
in reply to zphelps

Aah, yes...arterycloggingsaturatedfat. Kind of rolls off the tongue doesn't it. And the evidence for a causative link between saturated fat and heart disease is???

Meanwhile, the dietary factor that people should be concerned about that goes relatively unnoticed is elevated blood glucose/insulin levels, not just from sugar of course, but all digestible carbohydrates.

The stress aspect is with regard to how it affects your adrenal response and hormones such as cortisol. If your as stressed as you think, it may well be having a detrimental effect on your heart.

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Concerned
Concerned
in reply to Concerned

A stressor is anything that potentially disrupts your internal mileu

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zphelps
zphelps
in reply to Concerned

o.k.. adrenal glands deal with stress, if not it is a separate issue no?

how does the cholesterol leak into peoples eyelids and other areas and is visably evident?

My heart is all clear as checked regular by lipid clinc,,,

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Aliwally

Yes, very important to add that FH is not due to inflammation but known lack of LDL receptors. Was also reading that research from Norway indicates that in women the highest rates of mortality are at both the lowest and highest TC levels. Will try and find link as I can't remember all the details.

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Aliwally

The research from Norway is the HUNT study which shows for women the greatest mortality is with TC levels either under 5 or over 7 so most people with inherited disorders would fall in the over 7.

I personally hate this mania to get the cholesterol levels of the general population down still lower and lower, but people with FH fall into a totally different category.

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Concerned
Concerned
in reply to Aliwally

Thanks for that Aliwally. Help me out please. It appears to be an observational study? They appear to have identified some interesting findings, however what clinical studies have been done to isolate cholesterol as a variable responsible for lowering the mortality of people?

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Aliwally

Yes this study is a longitudinal population based study using questionnaires, interviews as well as blood and urine samples.

Norwegians apparently are one of the longest lived people but their score highly on traditional risk factors leading the researchers to suggest that the healthiest TC for Norwegian women is between 5-7, higher than currently recommended. Maybe it's the milk from an Omega 3 cow (Dr Kendrick joke).

No, off the top of my head I don't know of any studies isolating cholesterol. I tend to concentrate on studies involving post menopausal women with high cholesterol as the only risk factor and there are not a lot of them. CASHMERE is the only one and that had a lousy end point, only lasted a year and failed to get published in any mainstream journal.

I am not a statistician or a lipidologist, only a poor patient but I do try and do my research to try and decide what is best for me.

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Concerned
Concerned
in reply to Aliwally

Responsible approach

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