Heard of a CURE yet: Has anyone anywhere... - British Liver Trust

British Liver Trust

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Heard of a CURE yet

Ruby52 profile image
7 Replies

Has anyone anywhere heard of them coming anywhere near getting a cure yet for Cirrhosis -Fatty liver.

I no there is hope out there, as I was told I had 6mths left, My score was C decompensated liver.

Lots of bleeds. Had 9 bands. All dome. I was told last Nov, Give up drinking and never touch it again.

From that day I have never touched it, been back to see my consultant, I am now a B and feeling much better,I still have good & bad days,and yes I still have Cirrhosis & fatty liver. Well there's still hope out there, just don't give up,only if you want to.You have to want to do this, and it's a long road,but there is hope,after all I'm still here !!!

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Ruby52
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7 Replies

Hi

God knows if its a cure but I am on a trail using stem cell treatment it works with hearts they have had good results with rats on the liver, other that the wiskers ! it has been an interesting journey over the last 3 months, to early to say if it has had any effect, but live on in hope

Ruby52 profile image
Ruby52

Oh thanks Dave. The only cell's I have herd of Is on the TV cell block H lol no really I don't no much on the cell side.

It seems a shame that to come this far and just can not get rid of that last bit lol. Have you got the same as me!!! You don't no you have this until It's to late, or if you have a blood test before hand, mine was a massive bleed out, almost went that night, but like yourself still here. As on here we don't know who we are talking to, do you belong to our group called living with cirrhosis if not you can get on it thought invite only. let me no at= frans28@live.co.uk=

There’s still a lot of confusion across the nation about whether or not marijuana is effective for cancer patients. Odds are you’ve heard something about it but weren’t sure whether the information was reliable or definitive. So, in order to help clear things up, here is a list of 34 studies showing that marijuana cures cancer, categorized by the type of cancers being cured in each study. As you sort through the articles, note that the consistent theme between them is that cannabis shrinks tumors and selectively targets cancer cells. As bills and voter initiatives to legalize medical marijuana spread from state to state, remember that we’re not just talking about mitigating the side effects of chemo (though this is another viable use), we’re talking about curing the cancer itself as well as preventing its spread. I’ve taken the liberty of only including articles from credible scientific journals, removing any biased or otherwise improperly cited studies. Enjoy!

Cures Brain Cancer

nature.com/bjc/journal/v95/...

ncbi.nlm.nih.gov/pubmed/114...

jneurosci.org/content/21/17...

jpet.aspetjournals.org/cont...

mct.aacrjournals.org/conten...

Cures Mouth and Throat Cancer

ncbi.nlm.nih.gov/pubmed/205...

Cures Breast Cancer

ncbi.nlm.nih.gov/pubmed/208...

ncbi.nlm.nih.gov/pubmed/180...

ncbi.nlm.nih.gov/pubmed/219...

jpet.aspetjournals.org/cont...

molecular-cancer.com/conten...

ncbi.nlm.nih.gov/pubmed/227...

pnas.org/content/95/14/8375...

Cures Lung Cancer

ncbi.nlm.nih.gov/pubmed/221...

ncbi.nlm.nih.gov/pubmed/210...

nature.com/onc/journal/v27/...

Cures Uterine, Testicular, and Pancreatic Cancers

cancer.gov/cancertopics/pdq...

cancerres.aacrjournals.org/...

Cures Prostate Cancer

ncbi.nlm.nih.gov/pubmed/127...

ncbi.nlm.nih.gov/pmc/articl...

ncbi.nlm.nih.gov/pubmed/225...

Cures Colorectal Cancer

ncbi.nlm.nih.gov/pubmed/222...

Cures Ovarian Cancer

aacrmeetingabstracts.org/cg...

Curse Blood Cancer

ncbi.nlm.nih.gov/pubmed/120...

ncbi.nlm.nih.gov/pubmed/169...

onlinelibrary.wiley.com/doi...

molpharm.aspetjournals.org/...

Cures Skin Cancer

ncbi.nlm.nih.gov/pubmed/125...

Cures Liver Cancer

ncbi.nlm.nih.gov/pubmed/214...

Cures Biliary Tract Cancer

ncbi.nlm.nih.gov/pubmed/199...

Cures Bladder Cancer

medscape.com/viewarticle/80... (Sign-up required to view study)

Cures Cancer in General

ncbi.nlm.nih.gov/pubmed/125...

ncbi.nlm.nih.gov/pubmed/153...

ncbi.nlm.nih.gov/pubmed/153...

source:

wakingtimes.com/2013/07/27/...

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy.

AuthorsVara D, et al. Show allJournal

Cell Death Differ. 2011 Jul;18(7):1099-111. doi: 10.1038/cdd.2011.32. Epub 2011 Apr 8.

Affiliation

Department of Biochemistry and Molecular Biology, School of Medicine, Alcalá University, Madrid, Spain.

Erratum in

Cell Death Differ. 2011 Jul;18(7):1237.

Abstract

Hepatocellular carcinoma (HCC) is the third cause of cancer-related death worldwide. When these tumors are in advanced stages, few therapeutic options are available. Therefore, it is essential to search for new treatments to fight this disease. In this study, we investigated the effects of cannabinoids--a novel family of potential anticancer agents--on the growth of HCC. We found that Δ(9)-tetrahydrocannabinol (Δ(9)-THC, the main active component of Cannabis sativa) and JWH-015 (a cannabinoid receptor 2 (CB(2)) cannabinoid receptor-selective agonist) reduced the viability of the human HCC cell lines HepG2 (human hepatocellular liver carcinoma cell line) and HuH-7 (hepatocellular carcinoma cells), an effect that relied on the stimulation of CB(2) receptor. We also found that Δ(9)-THC- and JWH-015-induced autophagy relies on tribbles homolog 3 (TRB3) upregulation, and subsequent inhibition of the serine-threonine kinase Akt/mammalian target of rapamycin C1 axis and adenosine monophosphate-activated kinase (AMPK) stimulation. Pharmacological and genetic inhibition of AMPK upstream kinases supported that calmodulin-activated kinase kinase β was responsible for cannabinoid-induced AMPK activation and autophagy. In vivo studies revealed that Δ(9)-THC and JWH-015 reduced the growth of HCC subcutaneous xenografts, an effect that was not evident when autophagy was genetically of pharmacologically inhibited in those tumors. Moreover, cannabinoids were also able to inhibit tumor growth and ascites in an orthotopic model of HCC xenograft. Our findings may contribute to the design of new therapeutic strategies for the management of HCC.

PMID 21475304 [PubMed - indexed for MEDLINE]

PMCID PMC3131949 Free Full Text

Related CitationsShow all

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells.

Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation.

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway

Dorset123 profile image
Dorset123

Hi David,

Recently diagnosed with early cirrhosis, would be interested in the stem cell treatment. I know they are trying it for orthopaedics & other areas & it seems rational. Hope it's going well.

Reycloud profile image
Reycloud

Hi I'm 36 yrs old a female and also been diagnosed with liver cihrosis about 4/5yrs now They say it's a fatty liver for I am obese. Are cihrosis and fatty liver not the same? I had blood tsts and everything is normal. Not seeing a specialist just taking hydro codeine for pain. My doctor never sent me to a specialist . I'm confused

AyrshireK profile image
AyrshireK in reply to Reycloud

Reycloud, if you have Cirrhosis which is permanent scarring of the liver caused by any number of conditions such as your fatty liver you should definitely be seeing a specialist because with cirrhosis already and an ongoing liver condition your overall condition could be deteriorating.

LFT blood tests are often not an accurate set of tests once you have cirrhosis.

You should be at the minimum be getting blood tests every 3 months and an ultrasound scan of your liver and abdomen every 6 months. Cirrhosis can lead to all sorts of nasty side effects - my hubby has cirrhosis and portal hypertension with varices, he was only diagnosed last year and to date has had 3 ultra sound scans, 9 endoscopy's and 29 varices banded plus countless blood tests, a colonoscopy and more.

The ultrasounds check for further liver damage, keep an eye on the kidneys and spleen and for any signs of fluid build up and for any signs of lesion (sadly cirrhotic liver tissue can develop cancerous lesions and if picked up soon enough they are very treatable). We pushed for referral to the liver specialists in Edinburgh (our nearest liver transplant unit) and have been under their care since June of this year.

Don't just tick along taking pain killers (tablets in themselves can be doing more damage to your already damaged liver).

Push for referral to a liver specialist or your nearest liver transplant unit, even if you arn't a possible current candidate for transplant if you go under the transplant unit consultants they will keep an eye on your condition and if it becomes time for you to be assessed for transplant they are the folks who can make that possible. My hubby's care has been taken over by the transplant unit though they have said he isn't currently a candidate for transplant.

Take ownership of your condition, don't be palmed off with inappropriate care, push for referral to a liver unit and get your condition properly assessed.

All the best, AyrshireK

Reycloud profile image
Reycloud in reply to AyrshireK

Thank you for your information mam I will talk to my doctor :)

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