On treatment for gen 3 hep and after 1... - British Liver Trust

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On treatment for gen 3 hep and after 12 weeks have tested at around 12 which is barely positive.have I still got a chance of curing it?

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sjveitch12
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Bolly profile image
Bolly

Hi sjveitch. I think you have what is called an EVR, or Early Virological Response (12 Week PCR - >2 Log Drop). So yes you have a good chance of an SVR which is a Sustained Virological Response, in other words, undetectable level of virus at 6 months after the end of treatment. Its not until 6 Months post EOT that you are considered cured. So still with the treatment until the end, make sure you don't miss a dose, make sure you don't miss any clinic appointments or blood tests.

The best place on the internet for information and support for those with HCV is the Hep C Nomads forum. Find it at hepcnomads.co.uk.

By the way, most machines in the UK cant measure below 15, so a 12 is pretty much already undetectable. Well done.

sjveitch12 profile image
sjveitch12 in reply to Bolly

Hi bolly, thankyou for your reply and positive feedback. I was really concerned because in the first 4 weeks the viral load came tumbling down.but the last 8 weeks have only seen a drop of 5.you mentioned never to miss a dose and sometimes I have been missing evening doses of ribavarin.i just simply forget, so does this have a major impact on the possibility of achieving an svr?. I dont know your situation but once again thankyou.

Bolly profile image
Bolly

Hi again

As a Geno 3 there is no alternative treatment to fall back on if you fail this time around. Unless you were lucky to get on a clinical trial. Geno 1s have the protease inhibiters to add to the mix of Riba and interferon if they relapse or don't respond. So your first shot at the treatment, this shot, is your best.

Its easy to miss a dose if you are taking tablets from the box or bottle the pharmacy dispensed them in. I found the best thing is to get a daily pill dispenser from my chemist, (or online - they have them on Amazon) which has a section for every day of the week Monday thru Sunday. Put your daily meds in each section and then you can immediately see if you have taken them or not.

Try to avoid taking the Riba late in the evening if it gives you any problems sleeping. Some people find it makes them a bit speedy or gives them insomnia. Also its best to take the meds with some fatty food as it helps the absorption.

You will gets lots of tips on how to maximise your treatment on the hepcnomads.co.uk forum as its specifically for people with Hep C.

Keep on keeping on SJ. Yes the meds mess with your moods, they alter the serotonin levels. Its not your fault, its the meds. Many find it helps to take a course of anti-depressants while on treatment to counteract this side effect, and then when treatment stops you can stop the anti-d's.

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