Freezed : My trastuzumab vial was... - Breast Cancer India

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Freezed

Ch_balaji profile image
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My trastuzumab vial was freezed.on the box it was written " not to freeze reconstituted vial".what happens if freezed.does it looses its effectiveness.sir help me.

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Ch_balaji
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sumeet_shah profile image
sumeet_shahAdministrator

Yes, probably. Best to ask your Medical Oncologist. We don’t have Medical Oncologists on this forum unfortunately, so can’t guide you.

roxboxfox profile image
roxboxfoxRadiationOncologist

Trastuzumab must be stored at 2-8 degrees. Its efficacy is best at this temperature.

Outside this temperature with every 1-2 degree rise or fall... the Molecule disintegrates and loses it efficacy by 10-20%.

There is no way of knowing its efficacy unless if its tested in a reference laboratory in Sweden or US.