Have any of you been on Pertuzumab and Herceptin for longer than a year and if so what side-effects are you having? I am continuing to suffer from an itchy scalp, itchy neck and itchy forearms. I addition I have chronic diahorrea/IBS symptoms. More recently I have been feeling very tired and on some days a little light headed. The doctors don't seem to have any answers. The hot weather doesn't help the itching! I have been fairly stoical throughout my cancer treatment but after 2 1/2 years of various side effects I am finding life a bit difficult at the moment. Any info/advice, much appreciated!