Well when I developedbrain tumours as secondaries from her 2 + breast cancer I found out two things
In 2014 (old I know) the womenwiththeworstourcomes in New Zealand were her2 + and negative for oestrogen and progesterone - despite being treated with herceptin
I also just found out that 50% of women with her 2 positive breast cancer who develop secondaries do so in the brain - this is because herceptincannot transcend the blood brain barrier
So if you are Ger 2 positive - demand brain scans - I almost died because I didn't - it took a New Zealand oncologist tospot it!! Body scans are not enough.