My husband, who is a servere asthmatic,with indicators of irreversible damage, started seeing a new chest consultant last summer. Slo-phylin (theophyllin) at 250mg/b.d was added into his current drug regine.He takes 500mg of seritide b.d, flixatide 500mg b.d , teotropium, citirazine10mg, spireva 18mg, all once daily, monteleucast 10mg/nocte, nasonex 1puff b.d.
ThIs level of slophylin seemed to stop to fragility of hi sasthma,but his peak flow was only reaching 420 on a good day. We know he can blow 510. On revisiting the consultant, we expressed concern that my husband had started having an irregular heart rate with a racing pulse.This seem of concern to the consultant, who doubled the theophyllin dose, to the therapeutic dose of 500mg b.d. The symptoms then got worse with dizzyness racing pulse, up to 142dpm and the tackycardia worsened. It took me a number of weeks to talk hubby into going to the gp' s at this point I was expecting him to have a heart attack or seizureat any time. Eventually when he went to see the gp in late november the gp ordered blood tests, halved the dose of theophylin and wrote to the consultant. Initially I was pleased to have hubby refered to a young relatively new consultant who had trained at the Brompton. Now I am very anoyed that he ignored the feedback that he was give in September and has put my hubby at risk and a whole load of appointments/investigations to check on his heart. I used to work in the Pharmaceutical industry ,so I dont put doctors on pedestals, they are just like everyone else, able to make mistakes. However i feel this is incompetence as Hubbys tollerence of this drug is obviously low and he presented the side effects of poisoning which were ignored by the chest consultant. Thanks for reading as I needed to get this frustration off my chest without worrying Hubby. However I also want advice as to anyones experience of further addins so that a higher peak flow and an improvement his quality of life can be obtained. Thanks. S