I've had conflicting advice over this, a nurse told me they should be cleaned regularly, then a doctor said they should not be cleaned, they get 'primed' and work better. Who is right? And how often should a spacer be replaced? I use mine morning and night on two different inhalers, two puffs of each, so it is used 8 times each day. I am currently coming down on the side of it being 'primed', probably 'cos I'm lazy!