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Omeprazole

ZM1980 profile image
41 Replies

Has anyone been taking Omeprazole over a number of years? If so, have you experienced any side effects? I was previously taking them, then stopped due to concern over side effects, but considering taking them again as I feel reflux is affecting my breathing (history of shortness of breath, left - sided chest tightness - no evidence of airway inflammation on tests, Cardiac tests essentially normal).

Thanks

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ZM1980 profile image
ZM1980
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41 Replies
hypercat54 profile image
hypercat54

Hi I have been taking these for around 2 years now coz of acid reflux. I was getting bad indigestion too and was waking in the early hours 2/3 times a week and vomiting for hours into my toilet. Nasty!

There are other ones you can take though so maybe one of these would suit you better? x

ZM1980 profile image
ZM1980 in reply to hypercat54

Hi Hypercat, sounds like you've had a horrendous experience with reflux! I'm glad the Omeprazole have helped. I was taking Ranitidine for a while, which helped a bit, but I think the Omeprazole were more effective. Do you find reflux affects your breathing? x

hypercat54 profile image
hypercat54 in reply to ZM1980

Well I have mild copd and asthma as well and the pattern was waking up around 3/4 am coughing for England. Then I would start feeling nauseus too and would keep swallowing. After around 15 minutes the nausea got worse and eventually I would have to get up and throw up. This lasted for ages and was everything including bile. Only when this was completely finished could I return to bed.

I don't do it on the omezaprole. x

RoadRunner44 profile image
RoadRunner44

Hello, Yes, I have been taking Omaprazole for 5 years now. My doctor suggested I go on a lower dose which I did. Unfortunately the acid returned and I had to go back on 20 mg. I want to decrease the doseage of all the tablets I take if possible. I understand that we should only be taking them for a set period so I am going to speak to my doctor and ask advice.

ZM1980 profile image
ZM1980 in reply to RoadRunner44

Hi RoadRunner, yes this is what I'm trying to do aswell (minimize the amount/dosage of meds I'm taking), it's not always easy is it? I know with reflux there are surgical options, but even these have potential side effects/complications (although not so much with some of the newer procedures)

RoadRunner44 profile image
RoadRunner44 in reply to RoadRunner44

Hello again, As I said, I spoke to my doctor yesterday about Omaprazole tablets long term. He appreciated I wanted to reduce tablet dosage and suggested I take one 20 mg one day and 10 mg the next and so on. I'm going to give it a try and will feed back to everyone after I give it trial run.

ZM1980 profile image
ZM1980 in reply to RoadRunner44

Hi RoadRunner, hope all goes well with reducing the dosage of Omeprazole. I know it's better to do it this way, rather than stopping suddenly.

judg69 profile image
judg69

Been taking full dosage 15 years with no negative side effects. Best Wishes, judg69

AngieB72 profile image
AngieB72

Been taking them for over 10 years now with no side effects.

Gingerboy1960 profile image
Gingerboy1960

Hi ZM1980

I had to stop taking omeprazole due to stomach pains but now take pantoprazole which are very effective with no side effects!

I have taken them for a long time. I know there are concerns about long term use (e.g. osteoporosis) but reflux can cause problems too. I don’t want to tempt fate but they suit me very well i.e.. no negative effects.

Stephend profile image
Stephend

Morning

Been on them for years no problem been on 40&80 mg

Hope this helps

Ergendl profile image
Ergendl

Been on them for several years without a problem. I use a low salt diet with magnesium baths and plenty of fruit & veg for potassium to counter any mineral losses they cause. I was previously on ranitidine for many years but find omeprazole more effective.

Yatzy profile image
Yatzy in reply to Ergendl

I’m the other way round, omeprazol didn’t suit me, tingling mouth , puffy lips from the start, so have been on ranitidine for years now. Work well and no side effects that I’ve noticed.

If I forget a dose, I soon get a pain midway in my upper back. GP says stomach acidity shows that way sometimes. I’m assuming I’m on them for life, to counteract the acidity in steroids and oxytetracycline that are my regular companions. My osteopenia has been put down to steroid use, no mention at all of ranitidine.

Ergendl profile image
Ergendl in reply to Yatzy

It was my GP who took me off ranitidine when I was diagnosed with COPD, and prescribed omeprazole instead. He said the ranitidine was old fashioned.

Yatzy profile image
Yatzy in reply to Ergendl

Yes, I think that’s the general view 👵🏻

But does the trick for me, and I can buy a few Zantac in the chemist if I find myself out without my pills....two are the same dose as I’m prescribed! Years ago, my prescription came as Zantac, now just get the generic of course.

I’m odd with drugs so no surprise I reacted to Omeprazole, though GP said I was the first he’d ever heard of to have problem with it.

Have a good day 🌸

ZM1980 profile image
ZM1980 in reply to Ergendl

Yes I find Omeprazole more effective too, although they did seem to cause a 'dry feeling' in my stomach and osephagus (maybe need a lower dose). The mineral baths sound like a good idea.

Elpojohn profile image
Elpojohn

I,ve been taking Omeprazole since 1992, The only side effect might be hairloss , but maybe I would have gone bald anyway lol.

Pwkav1 profile image
Pwkav1

Been taking them over 10 yrs due to hyetus hernia. No problems for me at all. Hope this heps. Karen. Xxx

chubby2x22 profile image
chubby2x22

Like you I wanted to reduce all my meds. 3days without Omeprazole I was in agony. Restarted them and will definitely continue. Jane

johnderby profile image
johnderby

Hi, I've been taking them for about 10 years and no side effects. Good Luck. John

CFer profile image
CFer

I have been taking them for as long as I can remember. The doctors told me to stop them and other medications because I went into renal failure after a 2-week course of IV antibiotics. Within a day I was in real trouble with acid reflux , pain and nausea and I was begging them to put me back on them. They said I could have ranitidine ( Zantac ) but it didn't do the job. Luckily after a few weeks I stabilised and they put me back on them and I felt so much better.

ZM1980 profile image
ZM1980 in reply to CFer

Glad things are better now after what you went through with the antibiotics. I was taking Ranitidine, but agree they are definitely not as effective as Omeprazole. The rebound effects of acid reflux can be quite bad if stopped suddenly (or sometimes even gradually). They do seem to work well for a lot of people.

COPD123491 profile image
COPD123491

Hi ZM

I have been taking 40mg of Omeprazole for about 6 years now and I have not suffered any side effects. However my GP did warn me that the body needs acid and the overuse can have a detrimental effect on the system. In fact, he was loathe to prescribe them but did so because of severe reflux. I will continue to take them despite the warning as the reflux can be horrendous.

Good luck

Kevin

ZM1980 profile image
ZM1980 in reply to COPD123491

Hi Kevin, you're lucky to have an honest, informative GP - most I've been to seem to just issue these meds without afterthought! I have found them (Omeprazole) beneficial, though, despite some side effects. Suppose it's a case of seeing if the benefits outweigh the risks.

Titian8 profile image
Titian8

I took them on repeat prescription for over a decade, with no monitoring.

I now have osteoporosis, which is a known side effect I was unaware of.

These are very strong drugs and have been advised they should never be prescribed in first instance but if necessary only for a short time. This applies to all PPI's (so all the 'prazoles').

There are alternatives such as Slippery Elm, which after a while, are just as effective.

ZM1980 profile image
ZM1980 in reply to Titian8

Hi Titian8, sorry to hear you had such a bad time with the Omeprazole. I do think doctors need to consider the fact they can have potential side effects and monitor regularly. I do feel I need something to control the acid, as I feel it is affecting my breathing/lungs. Will look into the Slippery Elm, thanks.

Ergendl profile image
Ergendl in reply to ZM1980

I tried slippery elm instead, but did not find it worked for me - perhaps I didn't give it enough time. It is not the nicest of things to take: you make a thick porridge of the powder and tasting it is just like what it is, eating tree bark.

Titian8 profile image
Titian8 in reply to Ergendl

I totally agree with you Ergendl about the S.E in powder form.

Someone on this forum recommended to take it as a kind of porridge, so that it creates a barrier in the stomach against acid. I also found it difficult to take because of the texture and taste so bought the capsules instead. I do think the powder would be faster acting and more effective though.

The capsules took a while to kick in and experience the benefit (weeks in fact). However, I persevered and eventually they definitely worked for me.

ZM1980 profile image
ZM1980 in reply to Ergendl

Er, doesn't sound very appealing! Although I suppose that's usually the way with most things that are beneficial for you. I tried Aloe Vera juice before, which seemed to help a little, but not much.

Titian8 profile image
Titian8 in reply to ZM1980

Hi ZM1980, as per my reply to Ergendl: although S.E. Powder is probably the best form it's easier to start taking it as a capsule or tablet Trying it for the first time as a very thick drink would perhaps put you off.

An internet search of Slippery Elm will give you more information and options available.

I hope you get some relief as know how awful it is to cope with on a daily basis. Plus you don't want another serious condition to contend with, in the future, as a side effect of another drug.

Also try to sleep on your left hand side, as sleeping on right can cause acid production.

ZM1980 profile image
ZM1980 in reply to Titian8

Hi Titian8, thanks for the info - will look into the Slippery Elm capsules/tablets. I do find my reflux symptoms are usually worse in the morning and tend to subside a little towards late afternoon/evening. Otherwise it's chronic.

What brand and strength of Slippery Elm capsules/tablets do you take? How long did you take them before noticing relief from your symptoms?

Titian8 profile image
Titian8 in reply to ZM1980

Hi ZM1980, there are so many brands to choose from out there but I always try to find ones with the least additives, fillers etc so bought Bio Health Slippery Elm capsules online from Dolphin Fitness. You can also buy them from Health Food shops. I had originally bought NOW Slippery Elm powder from Amazon (both are vegetarian).

I can't remember exactly how long it was before relief totally kicked in, probably between 2 to 3 weeks whilst taking three times a day. I've got them on standby but hardly ever need to take any nowadays.

Nottobad profile image
Nottobad

I found Omeprazole very good was on it for about 3 years. Then had to come off it a few months ago as it reduced my magnesium level. Now taking ranitidine witch is not as good as Omeprazole

Ergendl profile image
Ergendl in reply to Nottobad

That's why I take occasional Epsom Salts baths, to help rebalance the magnesium.

ZM1980 profile image
ZM1980 in reply to Nottobad

I agree Ranitidine are not as effective as Omeprazole. Did you have regular blood tests to check magnesium levels or were you having symptoms consistent with deficiency?

Nottobad profile image
Nottobad in reply to ZM1980

My gp said to me that Omeprazole was 99% effective and ranitidine was only 50% effective. I originally went to see my gp about pins and needles in my hands and feet. She asked for blood tests and and the test showed y calcium was low. So she put me on calcium supplements. Then a week later I had a phone call at 9.30 in the evening from my local hospital saying that according to a blood test I had done in the community. My magnesium level was really low and with my calcium being low as well it could effect my heart. And would I come in to be put on an IV drip. And have a echo done as well . My magnesium level was 0.40. So after I had the drip. I haven’t had anymore pins and needles in hand and feet. Also not had Any more cramping. After the drip my magnesium level went up to 1.25. And they were happy with that. I am waiting to see a consultant at the hospital in the endocrine clinic. I also have to take calcium supplements.

Fennella02 profile image
Fennella02

I think they’re generally very well tolerated. I’m sensitive to many meds but this one is ok. It can cause your B12 to fall over time which is worth bearing in mind but it’s very easily rectifiable with appropriate supplements.

Titchykath profile image
Titchykath

I have been on it for 4 years , didn’t really have side effects. What are the most common ones?

Took it for 10 years for reflux I never had. Over the years, suffered from agonising cramp in the inner thigh muscles (worse than gall bladder pains) that lasted up to an hour, usually leaving me stranded up a mountain when hillwalking or search dog training or on some hillside when orienteering. Eventually realised the cramps started about the time I started omeprazole, so stopped taking it. As soon as I did, I lost the long lasting cramps I can still get the same cramps, but they only last a few minutes

Copey399 profile image
Copey399

I tried Omeprazole for acid reflux and (not to be too graphic) I couldn't move far away from the toilet and had many "accidents" - not nice. Went to my GP and she gave me Lanzoprozole which has the same effect. She just told me that it was likely that all those type of meds would probably do the same and just gave me a script for Gaviscon which I now just buy over the counter. It helps a bit when I have an attack but luckily it's not that often now.

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