Survival With Sirolimus Plus Tacrolimus Maintenance Without Induction Therapy Compared With Standard Immunosuppression After Lung Transplant

[2greys]

Question Which immunosuppressive strategy is associated with the highest survival in lung transplantation?

Findings In this cohort study of US recipients of lung transplants, sirolimus plus tacrolimus was associated with significantly better conditional survival from 1 year after transplant compared with mycophenolate mofetil plus tacrolimus (median survival, 8.9 vs 7.1 years after transplant). The highest conditional survival was observed in patients receiving sirolimus plus tacrolimus with no induction therapy (median survival, 10.7 years), which was significantly better than survival for those receiving mycophenolate mofetil plus tacrolimus with induction therapy (median survival, 7.4 years).

jamanetwork.com/journals/ja...

[Hacienda]

Thank You 2gs, Very Informative, You are such a Huge help with your Excellent Studies. Carolina XXX

[seyre]

Hi I had my transplant over 5years ago, now living a fantastic life. Immediately after the transplant I was on cyclosporine unfortunately after a short time I was showing signs of rejection so put on tacrolimus which I have been on ever since. Pleas Don.t hesitate to contact me if any further information is needed.

[Hacienda in reply to seyre]

Great that you are having a Fantastic life, Well Done Another Hero on our Forum, Thanks for sharing. Hugs. Carolina XXX