Mom has boops...I have a neuropathy and make and use liposomal curcumin...looked it up to see if it could help mom...found this, and she is starting it today!: (sorry, the website formatting shoved the whole thing together and you'll have to cut and paste the links)
COP/BOOPS and CURCUMIN
From European Respiratory Journal article "Cryptogenic organising pneumonia"
DOI: 10.1183/09031936.06.00013505 Published 1 August 2006:
"Some insights into the pathogenesis of organising pneumonia may further be extrapolated with acceptable likelihood from studies in the other infiltrative and fibrosing lung diseases, especially acute respiratory distress syndrome (ARDS; which is characterised by two successive stages of diffuse alveolar damage, namely acute exudative and chronic organising) 20, 21, 60, 61 and idiopathic pulmonary fibrosis (IPF) 62.
Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome.
From the abstract: "This data strongly supports a role for curcumin in modulating the pathogenesis of viral-induced ALI/ARDS in a pre-clinical model potentially manifested through the alteration of inflammation and myofibroblast differentiation."
(ncbi.nlm.nih.gov/pubmed/234...
Idiopathic Pulmonary Fibrosis & Curcumin
From the abstract: "This is the first study to assess the role of curcumin in IPF internationally. Curcumin has shown significant theraputic value in patients with IPF. No side effect were noted with the dose of 500 mg tid and was well tolerated."
atsjournals.org/doi/abs/10....
(also from same journal) "" Therefore, intra-alveolar fibrosis of organising pneumonia represents a unique model of inflammatory lung disease 20, 21, offering many similarities with the process of cutaneous wound healing 22.
Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats. ncbi.nlm.nih.gov/pubmed/246...
From the abstract: "Histopathologically, the curcumin-treated wounds showed better granulation tissue dominated by marked fibroblast proliferation and collagen deposition, and wounds were covered by thick regenerated epithelial layer. These findings reveal that the anti-inflammatory and antioxidant potential of curcumin caused faster and better wound healing in diabetic rats and curcumin could be an additional novel therapeutic agent in the management of impaired wound healing in diabetics."
FURTHER:
"BOOP is characterized by the presence of granulation tissue in the bronchiolar lumen, alveolar ducts and some alveoli, associated with a variable degree of interstitial and airspace infiltration by mononuclear cells and foamy macrophages. "
Protective effects of curcumin on methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells
nature.com/aps/journal/v27/...
Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis.
ncbi.nlm.nih.gov/pubmed/226...
CONCLUSION:
"Our findings suggest that inhibition of SR-A-mediated oxLDL uptake and promotion of ABCA1-dependent cholesterol efflux are two crucial events in suppression of cholesterol accumulation by curcumin in the transformation of macrophage foam cells."
Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model.
ncbi.nlm.nih.gov/pubmed/194...
From the abstract: "In conclusion, the results of the present study demonstrate an anti-inflammatory effect for curcumin in the cotton pellet granuloma pouch test, possibly acting through COX enzyme inhibition, and further inhibiting the generation of inflammatory mediators such as TNF-alpha. These results point toward the usefulness of curcumin as adjuvant drug therapy along with standard anti-inflammatory drugs."
Liposomal Curcumin Recipe:
Ingredients: Curcumin, lecithin (powder or liquid) , distilled water.
Equipment: (Needed) Quart jar or blender, sonic jewelry cleaner, plastic spoon. (Helpful) candy thermometer, funnel
Heat 1 cup distilled water to 113 degrees (for better absorbtion. Non-essential)
Put water in quart jar or blender, add 9 Tablespoons powder Lecithin. (preferrably Non-GMO sunflower)
Shake vigorously for 5 minutes or blend for 1.
Let stand for 2 hours.
Reshake or blend mixture as above.
Add 1 T Curcumin.
Reshake or blend as above.
Pour in small sonic jewelry cleaner.
Run cycles to 12+ minutes (more is better), while stirring with a plastic spoon.
Bottle, refrigerate.
Notes:
For liquid lecithn use 1/2 amount. (Non-GMO Sunflower recommended) then adjust recipe to eliminate the 2 hour soaking process and make the product with no waiting.
Increase recipe by 1/2 to full small cleaner capacity. Ratio C. water/T. lecithin/T.curcumin: 1/9/1.
A recent study showed liposomal delivery inproves absorbtion X 19!
A funnel helps pour from the jewelry cleaner to bottle without spilling.
Add dry ingredients to blender slowly while it's running, through the hole in the top of the lid for best mixing.
Sonic jewelry cleaners are available on e-bay for $18-20, free shipping.
Curcumin (95% curcuminoid assay should be avail for inspection) is usually available in powder form online (ebay or amazon).
