I have had COPD for over 20 years, I gave up smoking 19 years ago. I also have osteoarthritis, Type 2 Diabetes, fibromyalgia and had my large bowel and rectum removed 15 years ago due to Ulcerative Colitis so, as you can probably appreciate I am no quitter. The problem bothering me at present is that I use Salbutamol inhaler and Fostair and Tiotropium all through a spacer, I have repeated cycles of Oral and Viginal Thrush. This has been going on for at least 4 years, I am being treated with Flucomazole which, obvious to me, isn't doing the trick. I take all precautions to prevent this problem recurring, but still have the problem. I have recently broached the idea of using a Nebuliser and hands were literally thrown in the air, saying that I'm not giving the treatment a fair go!! PLEASE could anyone help me?????