Bisoprolol

[Platypus6]

Hi

Does anyone take their medication in the evening?

[Chappychap]

Yes, my GP advised me take it in the evening because it makes me sleepy. However, we should each consult our own doctors before tinkering with medication.

Good luck!

[Carlg]

No I'm a morning person as I take another lowering drug in the evening.

[Hanibil]

was told by two different cardiologists to take it in the morning as heart doesn’t need it as much while asleep, and have to say they were right

[El-Tel1990]

aspirin and Bisoprolol in the AM

Statin in the PM

[Cherrelleford]

Hey I take 5mg in the morning and 2.5mg around 5.30pm x

[Lovefrance]

my surgeon told me it is fine to take Bisoprolol in the evening so I take mine at bedtime. But check with your consultant. We are all different!

[56dick19]

hi on on bisoprolol 10mg I take it about 1030 pm

[Becksagogo]

I take mine after dinner (I eat late) because I sleep through the side effects.

[Sljp0000]

I take 2.5 mg morning and 2.5mg bed time. I couldn't tolerate 5mg in the morning in one go so the GP agreed I could split it. Apparently it doesn't really matter when you take it.

[Markp7119]

yes take at night as didn’t feel great when in morning feel ok now

[ParrotLover22 in reply to Markp7119]

The very reason I asked my Doctor!

[Makitaman1956]

hi, I take 1.5 night ,2.5 morning. 😀.

[Harefieldfan]

yes. I do. Don’t know if it matters.

[ClairePap]

Hello, I take mine in the morning. I was told by my cardiologist that it slows the heart and your body does this naturally at night

[Molben]

I take 5mg in the morning and 5mg at night. My Cardiologist said to take it about 2 to 3 hours before bedtime as I had a had fast heart rate overnight. It worked, my heart rate is much better overnight now and I can sleep a lot better.

[NLGA]

I take 10mg in the morning 5 mg at night around 10pm

[watermill]

Thanks for that question. I can now have a more informed discussion with my doctor

[richard_jw]

Logic would suggest that you take beta blockers in the morning. The half life of Bisoprolol is 10-12 hours. This means that after that time there is half the initial dose "active". So if you take it in the morning, you would expect your heart - to be more active than in the evening/night, and so benefit more from the drug.

[Platypus6 in reply to richard_jw]

Hi I have just spoken to GP she said I can take it in the evening.

[fishonabike in reply to richard_jw]

not sure about that - if i read it right you are working on the understanding that if your heart is more active you benefit more from the drug?

my understanding is the the effect of beta-blockers is to slow and steady the heart muscle so how does that fit with your theory?

and although "logic" might suggest that it's best to take beta blockers in the morning, research indicates otherwise: bhf.org.uk/what-we-do/news-...

[richard_jw in reply to fishonabike]

Because you are more activew in the day. In my case, without beta blockers (bisoprolol 1.25mg) my rhr is 80-85, and if I exercise it can go as high as 130. With bisoprolol my rhr is 65-70 and if I am active, can go to 100-110. The beta blocker reduces the heart rate bot the RHR and if you are active, it tends to limit the rate to put less strain on the heart. At night, without Bisoprolol, my heart (resting by definition) is around 65. with the beta blocker, it is around 60 having taken the beta blocker in the morning.

That's the whole objective of beta blockers, to reduce the heart rate and put less strain on the heart. Most people really don't need that at night.

[fishonabike in reply to richard_jw]

sorry but i am still struggling to follow your logic - are you really saying that the harder you heart works the more it benefits from a beta-blocker? i ask because the findings of the study i referred to seem to contradict that

also, i feel that, unless you have specialist knowledge in that field, you should run the theory past someone who has the right knowledge and experience before broadcasting it

[richard_jw in reply to fishonabike]

You really must make your own mind up. I have outlined what I have been told by at least 2 cardiologists, and if you look at the BHF website, the youtube video they put there seems to confirm what I have been told. Bisoprolol and other beta blockers reduce your heart rate by reducing the uptake of adrenaline/noradrenaline by the heart in particular.

[fishonabike in reply to richard_jw]

i am trying to make up my own mind, which is why i have asked YOU a simple question to which there is a simple yes or no answer

BTW, if you refer to other material it's helpful if you add links or more precise pointers than "a youtube video on the BHF site" - there are many youtube videos on that site and many cardiologists are referred to there

[richard_jw in reply to fishonabike]

bhf.org.uk/informationsuppo... you go

[fishonabike in reply to richard_jw]

still no Yes or No though????

[richard_jw in reply to fishonabike]

medicine is like that. In my case, the objective of taking the beta blocker was to allow my heart to recover from the MI. It was explained to me that taking bisoprolol in the morning effectively acted as a limiter on my heart, so daytime use was when my heart would beat harder, so limit it. At night the beta blocker had been in my system for longer and was less effective, but that was OK because my night time demands were less.

I believe that bisoprolol is used for other reasons, I have seen people post on this forum who take 10mg. I suspect that would be for a different reason (heart failure, or to reduce BP, perhaps).

In my area there is a "go to" pharmacist at Frimley hospital. I have twice found their advice very helpful

[fishonabike in reply to richard_jw]

that sounds like the sort of answer a politician would give

it sounds very much like you are unwilling to commit to supporting your original premise that: the harder your heart works the more it benefits from a beta-blocker

in which case i wonder why you said it at all

[ParrotLover22]

Hi. I take mine in the morning. I did ask my Doctor if I could take them in the Night but he said it is far better to take them before or after Breakfast. Maybe different for you though

[fishonabike]

i take mine in the evening, because i found that this pattern suits me best

i was interested to read this recently: bhf.org.uk/what-we-do/news-...

[Platypus6 in reply to fishonabike]

Hi fishonabike thanks that’s an interesting read! I have spoken to my GP this morning she said take it morning or evening whichever suits me! Let’s hope it does I will try the evening 😩

[fishonabike in reply to Platypus6]

you might find that a pharmacist would be more helpful - it is their speciality after all!

[Jetcat]

I was told to take in morning, I suppose it’s whatever doctors says.?

[Reidsy55]

I was told to take it before bed to lessen the side effects. I take 5mg about 9:30pm.

[doktordru]

Fascinating to read the different experiences here - I'm on 2.5mg - specified mornings by Cardio Unit - so that's what I've been doing. As others have mentioned (and this seems to work for me) resting heart rate at sleep can drop to 39/40 so I assume that's why it's a morning drug, albeit I imagine the impact of the drug after a period of time becomes cumulative and less impacted/less immediacy from the time its taken?

[Blueflags]

Hi Platypus6, I’ve had AF and Multi focal tachycardia for about 12 years and find it quite difficult and depressing to deal with at times. I’ve had two ablations and since the second one have had fewer AF attacks. I still have all sorts of symptoms and have been taking Bisoprolol for a number of years. My consultant prescribed them for me to take in the morning, (I have been gradually increased from 3.75mg to 7,5mg) whilst I was on holiday I started getting a lot of Ectopic’s and so took it upon myself to try something different, so I took 1.25mg at bedtime and 6.25mg in the morning, it seemed to help my ectopic’s the following day. This may have been coincidence but worked for me. It’s so difficult to get to talk to, or see a GP/Consultant these days. C. Okay thanks. Good luck.