Log in
Ataxia UK
2,984 members2,878 posts

Clinical trial of Niagen for treatment of a neurological disorder.

So yesterday while just doing a general search I came across an old bit of news and a new clinical trial that I was surprised I had not previously uncovered. First the study:

-

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

ncbi.nlm.nih.gov/pmc/articl...

-

In the study researchers cured mice that had a genetically caused disorder that impacts the brain in much the same way many ataxic brains are impacted, and they did so by feeding the mice Niagen . . . not niacicn or nicotinamide . . . but nicotinamide RIBOSIDE, otherwise known as Niagen.

-

That's interesting right, but once again if only I were a mouse life would be great, but wait . . . there's more.

-

That idea has now been taken to the clinic and is about to be studied in humans:

-

Nicotinamide Riboside and Mitochondrial Biogenesis

clinicaltrials.gov/ct2/show...

-

So looks like pretty soon we should get some very interesting data on what NR can and can't do in HUMANS! Also interesting is that the dosage will be 10 mg/kg taken twice daily which for me would be about 1300 mg per day total. (Currently I'm taking 375 mg twice a day or 750 mg total.)

-

Anyways, for those that don't follow my posts regularly here is a link to a more complete discussion of Niagen:

healthunlocked.com/parkinso...

6 Replies
oldestnewest

Hi Sunvox

Will this benefit friedrichs ataxia

Reply

IF . . . and that is a big if . . . but if the trial shows Niagen can improve cellular health it would be beneficial for many neurological disorders including FA. It would NOT be curative, but rather something that MIGHT slow progression.

Reply

Thank you

Reply

Wow! Congrats! You've been writing about Niagen 4 ages. Do they have a final result? Is the discovery pertinent to ataxia??

Reply

No results yet, but the study is set to conclude in a few months so hopefully soon, and as I replied above, it could be beneficial for many conditions including most if not all forms of ataxia, but again at this time it is still unproven.

Reply

I see ...Thanx 4 your response. N

Reply

You may also like...