Ompreloze and side effects: I am on a... - Asthma Community ...

Asthma Community Forum

21,680 members24,466 posts

Ompreloze and side effects

elanaoali profile image
16 Replies

I am on a two month trial of ompreloze 40mg twice a day. This is week 6. While my symptoms of sickness of have gone, I still have a sore throat off and on during the day but the salty taste in my mouth has decreased.

So I think it's been a success. There is only one thing I have got constipated. So I bought lactose solution from the pharmacy which is helping a bit. I have a good healthy diet and drink plenty of water. Anyone else got any more solutions?

Written by
elanaoali profile image
elanaoali
To view profiles and participate in discussions please or .
Read more about...
16 Replies
HungryHufflepuff profile image
HungryHufflepuff

It’s really good to know it’s working for you. Everything seems to have side effects of one kind or another though 😞

Tropicana do a whole fruit juice which supposedly contains 50% more fibre than other juice. Otherwise prune juice if you like it? Hoping things continue to improve for you 😊

elanaoali profile image
elanaoali in reply to HungryHufflepuff

Thanks Hungryhuff but I unable to have orange,apple or prune juice. I have a condition of the bladder which means juice is out.

HungryHufflepuff profile image
HungryHufflepuff in reply to elanaoali

I'm sorry to know that. Can you eat soups? Green soup with cabbage, Brussels sprouts, spinach etc would be fairly high in fibre. And maybe this is just something I've convinced myself is true but, chocolate! Good quality dark chocolate works too. I hope you'll find something that helps.

elanaoali profile image
elanaoali in reply to HungryHufflepuff

Thanks for the further suggestions. I am sorry for not mentioning my long list of forbidden foods. Nonething acidic, no process foods ie sausages, no caffeine (chocolate is out), no yogurts but can eat veg til it comes out of my ears. I can eat dates and certain kinds of nuts(high in fibre I think)

Maybe I could try soup it would have to be homemade without tomatoes.

HungryHufflepuff profile image
HungryHufflepuff in reply to elanaoali

This must be quite tricky for you. Home made soup is good, or vegetable casserole, you could add in beans and lentils. 🍲

Very best wishes to you 😊

elanaoali profile image
elanaoali in reply to HungryHufflepuff

Yes it can be tricky but gives you a very healthy diet. Thankyou for your kind wishes

Ghoulette profile image
Ghoulette

I'm sorry that you have developed this side effect. Lactulose can be very good. It is one of the more gentle formulations on the market. I'm not sure what dose you are on, but maybe that could be increased? There are stronger alternatives available which, although can be bought over the counter, if you haven't used them before, maybe try them under the supervision of your GP?

There are products called Movicol, Cosmo-col, laxido, etc. They are all powder dissolvable in water. Like lactulose, they rely on having adequate water intake to make sure they work correctly. It is important to drink plenty of water each day. If possible, you could try gentle exercise too.

Hope this helps x

elanaoali profile image
elanaoali in reply to Ghoulette

Thankyou for your advice. I started using it about 10 days ago. I bought on advice I got from a pharmacy. I started at 15ml once a day. Now move to 15ml twice a day. I am trying to drink plenty of fluids.

I have an appointment in 10 days time to review the medication.

If I still struggle I will of course mention it.

elanaoali profile image
elanaoali in reply to elanaoali

Had my appointment to review my ompreloze trial of two months at 40mg twice a day. GP deem it a great success.

Still have sore throat but not sure it's due to either a remance of a cold last week or oral thrush. So I waiting to see if it resolves itself.

So plan going forward is to reduce to 20mg twice a day instead of 40mg twice a day. I started doing this two days ago for a month then maybe down to 20mg once a day ("If feeling brave" doctors words)

The GP said I have complete freedom to increase back up if acid reflux comes back. I was reassured that being on ompreloze long term even at 40mg twice a day is safe. I had a concern about my bone density could be effected by this drug. Doctor didn't think it was a problem. Advise instead vitamin D tablets which I am quite wiling to do.

Still sticking to acid reflux diet but have fallen off the wagon a few times. Fatty foods ie. Chipshop chips ☹️ and fatty meat (lamb) really bad indigestion which no glavison will touch.

So adding another repeat prescription to my list and as my mum says if you shoke me I'll rattle!?

HungryHufflepuff profile image
HungryHufflepuff in reply to elanaoali

It’s great news this seems to be working so well for you. Hopefully it all continues to be so good with the reduced dose.

I’ve started taking vitamin D3 + K2 because the K2 apparently helps better absorption.

I hope you get better from your sore throat very soon and it’s nothing too worrisome. 🤞

elanaoali profile image
elanaoali in reply to HungryHufflepuff

Thanks Hungryhuff. Interesting what you said about vitamins.

I take you rattle too😉

elanaoali profile image
elanaoali in reply to elanaoali

After reducing my dose down to 20mg twice a day from the 40mg twice a day the symptoms of throat throat is back.

I rang my doctor's for advice (last Friday) and the duty doctors suggested I could try 20mg AM and 40mg PM. So did this and it hasn't worked.

So I going back up to 40mg twice a day from today and have a doctors appointment next Monday.

HungryHufflepuff profile image
HungryHufflepuff in reply to elanaoali

How disappointing that the lower doses don’t work. Are things starting to improve again now that you’ve increased the dose back up to 40mg? I hope things start to get better again soon 🤞

elanaoali profile image
elanaoali in reply to HungryHufflepuff

Thanks for your kind wishes. I am not giving up yet. I only started going back up with tonight's dose. I expect it will get better quite quickly.

elanaoali profile image
elanaoali in reply to elanaoali

After increasing my dose of ompreloze back up to 40mg twice a day my symptoms settled down.

I then went back to the doctors (two weeks ago) for

a review of my medication. I told the doctors about what happened when I reduced the dose. His advice was to stay at 40mg then try and reduce again to 20mg am and 40mg in two weeks time.

Times up on Monday so I am hoping that my body will tolerate a reduction of my dose.

The sore throat turned out to be laryngitis and is alot better.

HungryHufflepuff profile image
HungryHufflepuff in reply to elanaoali

I'm glad your sore throat is better and was unrelated to the reduction of ompreloze. That's one less thing to worry about I suppose. I hope your next reduction of the dose goes better this time 🤞

You may also like...

Side effects of steroids

it weaken your blood vessels? I have just found out that I have a couple of small bleeds/leaks...

Side effect of prednisolone

weeks. Then a reducing dose back down to zero. Nine days ago I had a blood test to check my blood...

Flu vaccine side effects

headache and muscle aches which I couldn’t shift. Day three today and the headache is thankfully...

First Post - Inhaler side effects worth it?

respiratory health. Despite having outgrown childhood asthma, it seems to have made an unexpected...

Side effects of Relvar Ellipta?

wonder if anybody has got any side effects from this medicine? Apart from asthma, I have problems...