Hi all, I've just had a follow up with my gp. I have been on theophylline for the best part of 30 years but for the past 6 months or so I'm having difficulty in getting my asthma back to being controlled, so my gp has prescribed this change. Just wondering about your experiences with this drug. I have a four week trial.
Theophylline vs montelukast - Asthma UK communi...
I used to be on both but came off montelukast last year. I did get some benefit from it initially but unsure if I still was by this point as it seems it can become less useful. My consultant felt as my asthma is not allergic it perhaps wasn't needed. I'm still trying to work out if it helped - I feel my day to day is not as good and he was a bit harsh on montelukast which can help some people.
I am also on theophylline (Phyllocontin) and had some civilised arguments about it as cons and others in team don't like it. I have argued to keep it as it works for me without side effects. Not sure why you can't just have both as they have different mechanisms, if your asthma is getting less controlled. Could ask to go back on theophylline alongside montelukast if you feel the montelukast helps but doesn't do it all? You may be looking at a referral by then however if still not controlled. Do you also take a steroid/long-acting reliever inhaler?
By all means give it a try if that's what you're being advised, but be aware that Montelukast can affect your mood - very seriously. Search "Montelukast neuropsychiatric side effects". If you start taking Montelukast and then notice that perhaps you're getting nightmares, or beginning to feel low for no apparent reason then stop taking it and go back your prescriber. I was taking it for several months towards the end of last year, and I only wish that I'd made the connection between Montelukast and depressive illness earlier than was actually the case.
Montelukast started to improve my peak flow after a couple of weeks. The weird dreams started more or less at once, the more serious nightmares came perhaps after a month, the suicidal ideation, and the "curled-up-in-a-ball-on-the-floor-screaming-in-terror" episodes hit me after about six weeks. Once a very sharp GP Registrar had made the connection and the Montelukast was stopped, I was significantly better within two weeks. But it took a course of CBT (now finished), plus anti-depressants (still being taken), to get me back to work. At one point I was getting daily contact from the mental health services. 'Tis only my very personal view of course, and I'd say that Montelukast is worth a try, but to be ready to bail out at the first sign of trouble. Other people will notice the changes before you realise it yourself.