Hi, I've recently been swapped from Symbicort to DuoResp and after getting quite ill I was swapped back. I would be interested in others experience. DuoResp states that although the dose content is lower the delivery system delivers a higher amount and therefore is just the same. However I always had powder in my mouth after use, I found the inhaler difficult and uncomfortable with sharp edges. The cost difference is £40 to £32 which is significant on 2 per month but I finished up with a paramedic visit and a bucket load of drugs after my only ever serious exacerbation. Lots of health bodies are advising the swap on cost and I would like to challenges their claim if others have had the same experience.