Hi, I've been asthmatic all of my life and now I'm 54. I've been on every possible inhalers of both separate and combination inhalers . I take Singulair nightly , have a nebuliser , xolair injections 600mg, 4 every 2 weeks for 2 years . I can not no matter which inhaler I use gain control day to day and have bought Ventolin tablets over the internet which I was prescribed years ago. They have added Seebri and tried the other COPD inhaler and only make me cough. I feel despite: xolair I'm having, regular chest infections, currently have pneumonia and can't get any relief breathing except taking lots of puffs of Ventolin, which then causes anxiety feelings and marked tremors of my hands. I feel so depressed as I thought xolair would help, Symbicort 400 /12 was changed to duo resp and I've just read the steroid in seretide is stronger . Is anyone else like me can't get control no matter which inhalers or how many puffs and yes tried smart regime didn't work . I'm convinced the steroid and combination inhalers make me cough and breathing worse. But after 52 years it seems so much worse . Any others out there ? ?