Sorry if this is an inappropriate question.... I am probably being really paranoid but on the information leaflet, for Symbicort, it says to use with caution if you take amitriptyline. I have been using a 10mg dose to help me sleep for a while and am also on Symbicort recently changed from Seretide. I asked a pharmacist and he said not to worry. I don't want to bug my GP but I'm taking pred as well at the moment and can't possibly believe than none of them interact. Just looking for perhaps a bit of reassurance!?