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Prednisolone and the sweats!!

Hi everyone, I have a slightly embarrassing problem. I am on my second course of prednisolone in 3 weeks, and I am suffering terribly with sweating all day long!! Also, my Irritible Bowel Syndrome is playing up too. Has anyone else got this problem, or is it just the weather or one of those things? If anyone has any advice I would be grateful. P.S. My asthma started with a sore throat and sinusitis, is it possible that I have got Post Viral Fatigue? Has anyone got similar symptoms?


12 Replies

Hi EmmaC

Hope your starting to feel better. In answer to you question about the sweats, I've been on steroids for over a year now and amongst all their lovely side effects I also have really bad sweats- it's horrible!!It only seems to be my head/face/neck, but somebody else I work with who has severe asthma and has a lot of steroids told me that she gets really bad sweats and was told it was the steroids- . I find it comes in waves- not exactly glamorous!I'm afraid I haven't got any tips apart from the obvious things- I've had numerous courses of steroids but until the last few months have never had a problem with sweating...I hope it settles down for both of us very soon!!Good luck, take care




Me too........I have been on steroids for 18 months about and I suffer from horrid sweats....Head (especially top of it)/neck/back (it trickles down my back, its awful) and my legs....Doesn'thelp cos i suffer from eczema too and the sweat aggrivates it....I know its horrible and I suffered really bad from the sweats and felt dirty in a way because I had back surgery and wasn't allowed to get my wound wet whilst it were healing that I couldn't bath or shower for 2 months either, yuk, lol....

I would love to get rid of the sweats cos it makes me feel dirty and so paranoid about smelling yukky ( btw I can have showers now lol)....

Take care x


Thanks sam1980 and fi, So it seems that it could be the preds that are causing these horrible sweats!! I`ve only got ONE MORE DAY of the present course (with luck), to go now so perhaps they will start to ease. I know the weather has been pretty unpredictable lately, but these sweats have been ridiculous!!!! I hope all our sweats will ease soon. Keep well, EmmaC


yes another sweater here - definitely the back of the neck. I need to wash my pillow daily when it is bad.


Hi michaelesther, I have recently finished my second course of prednisolone, and so far I have seen an end to these serious sweats. Hope you all do too. EmmaC


Hi EmmaC,

Sorry to hear you're feeling so poorly. As you no doubt know, those little pred tablets can have all sorts of nasty side effects. Interestingly, excessive sweating isn't actually listed in the BNF as a side effect of pred, but I think the experience of the posters below speaks for itself!

I think if your symptoms persist, though, you should go and see your GP just to be on the safe side, as there are other things like certain infections, thyroid problems and so on that can causing excessive sweating. Sometimes being put on pred can reactivate certain infections that are dormant too.

I can relate because I have problems with excessive sweating on my face and head, due to a nerve problem called autonomic neuropathy. There are a few general things that you can do to make life a little more comfortable and a little less moist!

Obviously washing frequently is important but try not to get too obsessed and be hopping in and out of the shower every couple of hours! Sweat only smells bad when it's stale and bacteria have had a chance to work on it, and that usually takes a few hours to happen. I know that when you are sopping wet it's difficult to convince yourself that you don't smell, but by washing too frequently, especially with harsh soaps, you can actually make the problem worse. A mild soap or a soap-free cleanser will help the most.

Obviously using an anti-perspirant regularly is important (bear in mind that not all deodorants contain anti-perspirant ingredients, some just contain smell masking stuff). If using a normal shop bought anti-perspirant twice a day is not doing the job, your doctor might recommend one containing aluminium chloride - these can be bought in a pharmacist or prescribed. Please do read the label very carefully if you get one of these. They can be used all over the body, but some people find that they irritate the face, and they can't be used on inflammed or broken skin. Personally I find them too heavy and irritant to use on my face, so I don't use them, but I would consider it if I had sweating affecting other areas of my body.

Obviously wearing cool, loose, cotton clothes helps, and black or white are usually better at not showing up sweat patches. Some people find that spicy foods make their sweating worse, and obviously hot stuffy environments will also do so.

If you have persistant severe sweating of the head/face, armpits, hands or feet that is interfering with your life, and that is not due to medication or another medical condition (this type of sweating is known as primary hyperhydrosis) then your doctor may be able to refer you for consideration of keyhole surgery to cut the nerves which are causing the sweating, although this can have side effects and can cause sweating in other areas.

Phew.... after all that sweaty talk I'm off for a cold drink!

Hope some of this is helpful

Em H


Botox as seen on 'Embarasing Bodies' C4 series was used to help exessive sweating.


Hi All, Thank you for all your helpful posts. You have all been very helpful. Luckily, those terrible sweats have now ceased as I have finished taking my prednosilone. I am now feeling a lot better. Thanks again, EmmaC


What about sweats caused by other medications? I sometimes wake up covered in sweat and wonder if the medications I take could be the cause. Any thoughts?


Hi everyone I'm just ending these pills given for a rash. Yes those dang sweating spells! Does these pills throw u out of balance? It has effected my moods, pushed my blood pressure up, dry mouth and not sleeping. TY.


I am on on a short 10 day dose of prednisone. This is my second day of horrible sweating. I have never sweat like this. Oh and sleep... forget it!

1 like

Same here, I keep using a fan to take the edge of it. On second day of sweating now so hopefully this will be the last day of it 🤧😷😤


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