I am on a combination of meds for rheumatoid arthritis which I have been taking for just over a month now. Following my recent blood test 4 days ago I had a small bruise but this seems to be getting bigger and is now the size of a satsuma. I have also started getting small clusters of spots on both my cheeks within 24 hours of taking methotrexate. This gradually goes down as the week goes on then reappears again after taking it again. The other meds I'm on is prednisolone and hydroxychloroquine. I wondered if anyone else has had these problem when taking any of these meds and if so do they stop once your body gets used to it. Any help would be gratefully received.