The-science-of-senolytics-how-a-new-pill-could-spell-the-end-of-ageing

[monkeybus]

For a long time, I studied life extension. Was before my AMN hit. And it is a big thing on the Internet. I took plenty of pills, powders and whatnots.

Regarding AMN, I am of the opinion it is like we are prematurely aging. Our bodies are shutting down and exhibiting all sorts of maladies. A lot of things aren't rocket science. Move more, eat less, relax, go easy on the booze, forget the trans-fats, eat more fish, green tea, watch your weight, all that. Those things work for us as well as the general population.

I embraced the antioxidants-can-cure-people-just-like-they-did-for-mice thing, except it didn't work. Now I read this in the Guardian -

theguardian.com/science/201...

A simple treatment to stave off the health problems of old age could be available in five to 12 years.

Too much to copy/paste. A good read, it is all about removing senescent cells from your body. Removes decades from how old you feel.

If I could only turn the clock back ten years, I would be a happy monkey. Despite the fact we are all far from a cure, there are plenty of treatments on the horizon, none tailored to us, but quite a few hold a lot of hope for us.

EPI-743, Mito-Q, Sobiterome, ABCD2 upregulation, Minoryx, Crispr, antioxidants, peptides, now this. Google and Facebook are poised to dump Billions into medical research, and I haven't even mentioned China yet. I go there quite a lot, and I tell you, they aren't playing about, they really mean business.

Anyone have any more to add? We live in interesting times.

[tieaknot]

Wow! Intriguing!

[monkeybus]

Answering my own thread. That's how much I love myself.

I read years ago how old mice, given blood transfusions from young mice lived longer. Even has a name, Blood Transfusion Therapy. I asked my neurologist if I could have it done. He said no.

[JasonHarnum in reply to monkeybus]

monkeybus thank you for your insightful follow up on your own post!

[monkeybus in reply to JasonHarnum]

Cheers, Jason. Means a lot.

[Roker1176]

That's awesome you seem to be an expert do they so anything about hgh because is anti aging also regenerates cartilage I think the fact that professional football and basket ball players and actors like Sylvester Stallone for injuries and heal cartilage I think this would be fantastic for us AMN . Right now its too expensive and there are minimal side effects and it rejuvenates the pituitary gland to make us heal quicker and we are missing signals from the brain to back this could get that signal going again just like ampyra does

[monkeybus in reply to Roker1176]

I seriously looked into HGH. Very hard to get hold of, but the HGH releasing peptides are legal and freely available. In common usage in the bodybuilding community. I don't know if there is any evidence that it'd help us though. If there was, the MS people would be on it already.

[Roker1176]

There actually is evidence that hgh slows the progression and regeneration of cartilage that’s why I thought it was insightful

[monkeybus in reply to Roker1176]

Maybe.

Remyelination is the holy grail. Try -

www-researchgate-net.cdn.am...

Here is the pertinent bit:

We treated with GH many patients with MS (different kinds of progression and inflammatory activities). Results are good or very good in general, not for stopping the disease progression but for remyelination. In fact, GH stimulates the proliferation of NSCs inducing the formation of oligodendrocytes responsible for myelination. We did not publish any case yet because of the use of GH is "off label", therefore we could be punished by carrying out a "not authorized" clinical trial, but we saw many MRI in which multiple white matter lesions disappeared after GH treatment. Anyway, I have to insist, GH administration does not avoid the MS but myelinates lesions, as we saw with Schwann cells in rats with the sciatic nerve sectioned, treated with GH, they recovered fully limb function while saline-treated rats got paralytics:

Growth hormone treatment enhances the functional recovery of sciatic nerves after transection and repair.

[Roker1176]

Yes that’s the article I read

Good information isn’t it

[monkeybus in reply to Roker1176]

Very good. I am more than tempted to have a go. It's the injecting that warns me off.

[Roker1176]

They are injections in your stomach like insulin you pinch some fat very safe. I’ve tried it. Alison did you see the gemha research on here for stem cell for ALD patients looks fantastic