You may want to share the below research article with your medical team. It may contain information that they may not know, as was the case with my team.
The article discusses a correlation between men on ADT (hormone therapy) and the development of meningioma tumors (sometimes incorrectly called a brain tumor. This is what happened to me. After being on Lupron for 2.5 years and Zytiga with prednisone for about 16 months I developed severe headaches and brain fog. I stopped treatment (I was in NED), but could not convince my oncologist to run a MRI. Finally, a year later I was able to convince a neurologist to run a scan. They found that I had a 3.4cm “brain tumor “ in my left front lobe. If you have similar issues and are on hormonal therapy you may want to ask for a brain MRI (with and without contrast).
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Dr_WHO
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Wow…I was diagnosed with aPCA last Jan and they did a full body mri and found a benign meningioma on front left lobe as well but before any adt hormonal therapy. I had it removed (craniotomy) in Dec of last year as it was growing slowly. Maybe the Adt therapy caused it to grow.
Oh my gosh. So sorry you went through this and also glad you decided to share it. This is good to know. I’ll definitely pass this on to my father, who has been on hormone therapy. I’m curious as to why they wouldn’t run an MRI on you sooner? Take care & thanks so much again for the info.
Wishing our father the best. The chance of getting a meningioma from ADT is low, but it is still there. As for why it took so long to get an MRI - that is a long and sad story . From day one I had to fight my hospital for treatments for cancer. Having the same issues with the meningioma.
Welcome back. Dr. WHO you didn't post anything since 3 years. Good to hear from you again. Meningioma is a benign tumor and surgical resection is curative. Whish you all success fighting all kinds of challenges related to PCa.
Yes I have been away for a while. Dealing with my hospital was/is very draining to the point that I had to take a break. But when I found the above article I had to share it with the group.
"Our findings indicate that caution should be taken when considering LHRH agonist therapy for patients with PCa and a history of meningioma or concurrent meningioma." Interpreted literally, this indicates that no caution needs to be taken absent a history of meningioma or concurrent meningioma.Having been on ADT for a over two years, seems to me that there are almost-certain SEs that you just learn to live with, and some less likely but potentially severe SEs that you just hope you don't get.
Yes I agree that there are side effects. For me (diagnosed with Stage 4A Ductal Prostate Cancer) the side effects I like the most is that I am still here. I just wanted to share information that most oncologist are not aware of.
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