ADT and growth of breasts : I was not a... - Advanced Prostate...

Advanced Prostate Cancer

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ADT and growth of breasts

Mascouche profile image
28 Replies

I was not a victim of breast enlargement during my first injection of Lupron or while on Casodex but I do not know if it is any indication that my breasts won't grow once I start ADT again in a few weeks.

Did any of you experience growing breasts while under ADT?

If yes, did they go away after treatment, and how long did it take?

If no, was it through sheer luck or did you radiate your nipples or did you take Femara or some other drug to prevent breast growth?

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Mascouche profile image
Mascouche
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28 Replies
Mascouche profile image
Mascouche

Why are you saying that I've been a member for over 2 years? I registered here in September and then only came back and started to become a regular as of Dec. Two years ago I did not even know I had cancer. ;)

j-o-h-n is the breast man on this site.I'll defer to him.

j-o-h-n profile image
j-o-h-n in reply to

Thank you for the acknowledgment. Best way to avoid big breasts is to avoid eating in breastaurants.

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 01/15/2021 2:29 PM EST

More coffee is what you require

dhccpa profile image
dhccpa in reply to

Rx drug coffee?

in reply to dhccpa

Carry over from the Coffee and PCA post. I was just joking with Nal

dhccpa profile image
dhccpa in reply to

Whew! I was afraid you were proposing coffee by Rx only! Couldn't resist that one.

in reply to dhccpa

Yeah..I often wonder if my humour is received in the correct context. Ill carry over themes from other exchanges with certain members.

dhccpa profile image
dhccpa in reply to

A sense of humor is always welcome--SOC or Naturopathic.

Tall_Allen profile image
Tall_Allen

Gynecomastia is usually not a problem with ADT. It is only usually a problem when a man is taking Casodex monotherapy. With Casodex, testosterone continues to build up in the serum because it can't be utilized by cells. The excess testosterone is metabolized into estrogen, which encourages breast growth. Tamoxifen blocks estrogen in breast tissues. Femara is a bad idea- you don't want to eliminate estrogen entirely- you will feel awful if you do.

Mascouche profile image
Mascouche in reply to Tall_Allen

Good to know. Thanks.

bluesnjazz profile image
bluesnjazz in reply to Tall_Allen

Tall-Alan, I can confirm that. Was on Lupron & Casodex for 6 months, then off everything for a year, no breast growth. Then I started Casodex alone off and on for two years and during the time also started taking isoflavone supplements and within a few months I had bags of jelly on both sides, one so painful I had to wear an elastic band around them to keep them from bouncing when I ran. Stopped the isoflavone and they stopped hurting and stopped growing. They do NOT go away, though, without surgery, it seems.

Tall_Allen profile image
Tall_Allen in reply to bluesnjazz

Tamoxifen (20 mg/day) can reverse them if they are new. If they are established and small, cortisone injections can dissolve the mammary tissue. But you are right that if it is established and large, surgery is the only alternative.

joeguy profile image
joeguy in reply to Tall_Allen

I just started Casodex as a monotherapy because I had so many heart related issues while on Eligard/Firmagon. Its a shame it causes breast growth, because without the injections, there seems to be no tachycardia, skipped heart beats and rhythm problems. Doesnt Tamoxifen come with its own set of cardiac related SEs?

Tall_Allen profile image
Tall_Allen in reply to joeguy

I'm not aware of any heart rhythm side effects, and it's not listed as one.

joeguy profile image
joeguy in reply to Tall_Allen

Maybe its a clotting issue Im thinking of with Tamaxofen.

joeguy profile image
joeguy in reply to Tall_Allen

If I can get my insurance to approve it, Im going to give the new drug Relugolix a try along with the Casodex . Its appears to be very similar to Firmagon, but with a very short half life. My thinking is that will be better because if I do experience heart SEs again, I can stop taking it, and T should come back up quickly.

Mascouche profile image
Mascouche

When you say "Keep you bodies Estrogen/Estradiol low but not dangerously low"... Do you mean through a natural way (if so how) or through other drugs?

Mascouche profile image
Mascouche

I always do but sometime it helps to get a hint of what to start to search for. Now I know. Thanks.

BrentW profile image
BrentW

I now have a wonderful if small pair, after sixteen years on ADT. I lump them (pun intended) with getting in touch with my feminine side.

dhccpa profile image
dhccpa

My doc said I would gain weight and might grow breasts. But I switched to whole food plant based diet, lost 30 lbs. No problems after two years. I also dropped alcohol, meat, dairy, doft drinks, artificial sweeteners, and processed/refined products.

Mascouche profile image
Mascouche in reply to dhccpa

Your road is similar to min. I was 210lbs in Jan 2020. I dropped all that you've dropped and I now weight 153lbs in Jan 2021. I did not get any breast growth during my first try on Lupron but I didn't know if it was because I was lucky or because I had not been on it long enough.

dhccpa profile image
dhccpa in reply to Mascouche

I've been on Lupron continuously since 11/2018. Started dietary changes 7/2019. But I exercised regularly on through. May be a little bit of everything. My overall SEs besides loss of libido have been minimal, although I worry about LT effects of ADT.

Mascouche profile image
Mascouche in reply to dhccpa

Yes osteoporosis, Alzheimer, heart disease and the likes that are caused by extended use of ADT are nothing to look forward to even if they are better than death. However I know that statistics are a sum of all kinds of people, most of which do not change anything and just follow the allopathic treatment. I am hoping that for people who do WFPB, exercise and supplement themselves adequately with all of the minerals might avoid being afflicted by those bleak outcomes.

dhccpa profile image
dhccpa in reply to Mascouche

I sure hope so!

Yep but there is no way I'm breaking those K cups apart everyday.

tarhoosier profile image
tarhoosier

15 years from diagnosis here. After several periods of ADT I had moderate breast growth. After Salvage radiation I went more than a year with rising T and no psa so I scheduled breast reduction surgery. My oncologist had listed diagnosis code for gynecomastia on my records for a few years and I believe this is why Medicare covered the cost. I would have paid for it myself if necessary, about 6,000$ at the time. That was six years ago and with return of psa and further treatment the growth returns but starting from zero means it is no more now than before surgery. If I feel I need it again I can do so.

TEBozo profile image
TEBozo

My breasts increased in size due to weight gain on Lupron and Zytiga and Prednisone.

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