Well I finally got my 15 minutes of fame.

[Costarica1961]

Good day gentlemen. As some of you may know I am involved in a phase 1 clinical trial. Harpoon at OHSU. I finished my 3rd infusion and was anxiously awaiting going home after 9 hours at a outpatient facility. Unfortunately I had a 103 fever and a very low pressure. So I waited and waited, finally they admitted me into the E.r dept for observation. A blood lab was done and my liver enzymes ast was 2152 my all phos was through the roof, well this gunea pig data went nationwide in the medical circles according to Dr B they have never seen number so high with at least this study. Luckily they have slowly gone down . Had to miss a week of infusion and my dose will be reduced going forward. I am having radiation to both humerouses tommorro , I have tremendous met pain. I have seen my bone scan from Aug 10 and I have joined the paved club. Hoping immuotherapy will help, trying to stay positive and keeping my eyes on the possible end results.

[Tall_Allen]

Sheesh. I hope it's true that what doesn't kill you makes you stronger.

[Costarica1961 in reply to Tall_Allen]

I am one tough lab Rat.

[Hidden in reply to Costarica1961]

They don’t know who they are f n with !💪

[tango65]

Sorry to hear you had such a reaction to the treatment.

You are really brave to go into this type of trial, thanks.

Best of luck on your journey.

[Costarica1961 in reply to tango65]

Brave or desperate, either way I'm in it too win it.

[Hidden in reply to Costarica1961]

Hope is that it is deleting the p c?

[George71]

Sorry about all the problems, hang in there. It sounds like it is getting better and you will get good response to the treatment.

[Costarica1961 in reply to George71]

I hope so, cause this is no picnic.

[timotur]

You’re a true warrior, stay strong! Best wishes for your treatment. 🤞

[Costarica1961 in reply to timotur]

Thankyou. You as well

[Kaliber]

Wow those are jaw dropping numbers ... herze hoping that met pain is gone pronto ... I smell some rads and Fentanyl in the wind. Keeping my good thoughts for you brother.

I was in a clinical trial once ( not ) ... instead of Harpoon , it was called “ Lampoon ( was gonna say tampon but changed my mind ) “ .... in my trial, everyone was given the placebo.

Just say’in 😂😂😂😂💪💪💪👍👍👍🌸🦋❤️🌼🌈

[Costarica1961 in reply to Kaliber]

I feel like I have been harpooned. But this too shall pass.

[Kaliber in reply to Costarica1961]

Boy howdy it sounds like it . I have a bit of met pain myself buddy, my heart really goes out to you. I’m rooting for effective pain management ASAP for you. We all have too much on our plate already, we absolutely deserve , at the least, pain free palliative and hospice eras of our lives. Let’s get those docs crank’in. and do their jobs and get that fixed .... it’s very doable . Quicker is better.

Best wishes brother 💪💪💪💪👍👍👍❤️❤️❤️

[MateoBeach in reply to Kaliber]

Anyone know how I can get a good placebo outside of a clinical trial? Seem to be as food as many other treatments with lower side effects. 🤣🤣🤣🤷🏼🥂

[Kaliber in reply to MateoBeach]

Yayahahahaya yayahahahaya yayahahahaya .... you’re right , a really good placebo , with absolutely nothing at all in it , is really hard to find. I hear there’s a place down in the the SOMA in S.F. , that in early evening when the streets are packed, where you can buy “ pure “ placebos. You can do half a hit of one of those and get the same results as three regular placebos.

Just say’in 😂😂😂😂😂❤️❤️❤️

[Hidden in reply to MateoBeach]

Hahah😂

[dmt1121]

You have gotten everyone's attention. That's not easy! Please stop spiking your infusion IV. It could be dangerous!

Kidding aside, you are doing all you can. I knew someone I worked with a few years back on an immuno-therapy treatment for melanoma that had invaded every part of his body, including brain and liver. The therapy literally almost killed him. He had to be brought back from his treatments in Portland to Medford (5+ hour drive) in an RV to allow him to lie down the whole way. He could barely walk when he came back to the office. Everyone thought he was done. He fully recovered with recurrences that were treatable when they occurred. He had a 15% chance!

So, stay the course. We are with you and DO stay as positive as you can because the mind is an important part of the equation for anyone trying to get well.

Please let us know how you are doing when you have time and feel up to it. Take care.

[Hidden]

Please, Let’s not do that again? Does anyone know why? Just an adverse reaction? I m pulling for you to stay away from the hospital ....

[Patrick-Turner]

15 minutes of fame is better than I have ever managed, 15 seconds maybe, at age 23, when some dude on a building site said "Maate, youse is de man hoo they can't root, shoot, or electrocute.."

I have the dubious honour of being a "pinnup boi" because someone said I was healthiest stage 4 cancer patient at the Canberra Hospital.

From what you say, you seem fairly OK with the idea that "life wasn't meant to be easy."

There was a Prime Minister here in Australia in 1983 who was infamous for saying this before and election, and he lost. Voters don't like being told some things.

I wish you The Best Of Luck,

Patrick Turner.

[dadzone43]

Wretched experience. Positive thoughts going forward.

[Faith1111]

It’s clear you have a lot of positive thoughts being sent. Best wishes going forward

[Jackpine]

Costarica1961,

You are one tough lab rat more power to you brother!!

Stay strong and praying things improve!!!

[Stevana]

I too am in an immunotherapy clinic trial. It’s in phase 2 using docetaxel and nivolumab for mHSPC patients. It’s kind of kicking my butt, but nothing like you’ve experienced. I just had the 2nd cycle of six infusions every three weeks. I hope I’m not in for the rougher ride you've just experienced. I have to say I’m pretty weak right now but staying the course. My worse SE is thrush which I’ve been taking nystatin for in an attempt to get it under control. Not much of an appetite when your mouth is raw and you can’t taste anything. I’ve dropped about 10 pounds so far. One bit of advise (not that any of you would be so stupid) don’t have your uvula removed during chemotherapy. Mine had been giving me problems, becoming elongated and causing me to choke when I slept, so I went to an ENT guy and he clipped it out on my initial visit. He also told me it would heal in about three days. I’m now finding out it could take up to three weeks. Not something you want to deal with during chemo and with thrush at the same time. I hope to be out of the woods by the time my next chemotherapy session comes around.

I wish you all the best going forward and that the worst is past you. Stay strong. That's what I’m planning to do, but sometimes easier said than done.

[monte1111]

If I have a uvula, I certainly ain't getting it clipped. Sorry you are going through such crap. Great post. I hope it doesn't hurt when you laugh.

[j-o-h-n in reply to monte1111]

I DIDN'T WANT YOU TO MISS THIS:

What is the purpose of a uvula piercing?

The jewelry will also pull the uvula down during sleep, reducing the diameter of the nasal airway and increasing the chance of sleep-related breathing disorders such as snoring. Uvula piercings may migrate leading to bisection of the uvula, which is harmless.

I'm Good........

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:05 PM DST

[monte1111]

By the way, I hope you get 15 more years of fame. Enjoy.

[Stevana in reply to monte1111]

Everybody has one. It’s the little punching bag that hangs from the roof of your mouth. It’s really useless anatomy that was interfering with my sleep. My regret is the doc told me it would heal in three days so I said why not? Turns out it’s going to be a much longer healing time and is quite painful to swallow. I’ll get thru it, but I didn’t need the extra misery I brought upon myself. Thanks for the condolences. Hoping you get 15 more years of fame yourself.

[j-o-h-n in reply to Stevana]

What is the purpose of a uvula piercing?

The jewelry will also pull the uvula down during sleep, reducing the diameter of the nasal airway and increasing the chance of sleep-related breathing disorders such as snoring. Uvula piercings may migrate leading to bisection of the uvula, which is harmless.

I'm Good........

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:02 PM DST

[j-o-h-n]

900 seconds of fame, 86,400 seconds of pain...congratulations?

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 6:43 PM DST

[SPEEDYX in reply to j-o-h-n]

Rent 525600 minutes that's the way to go!!

[j-o-h-n in reply to SPEEDYX]

With Section 8.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 6:57 PM DST

[SPEEDYX in reply to j-o-h-n]

I figure you qualify for that

[j-o-h-n in reply to SPEEDYX]

BLM-MF

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:07 PM DST

[SPEEDYX in reply to j-o-h-n]

I thought it meant Message Forthcoming...which it did come!

[j-o-h-n in reply to SPEEDYX]

That's what I like about you, you're so Mighty Fine.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:26 PM DST

[j-o-h-n in reply to SPEEDYX]

BTW the MF = My Friend....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:16 PM DST

[SPEEDYX in reply to j-o-h-n]

My Friend =My Brother

[j-o-h-n in reply to SPEEDYX]

You know if you were my next door neighbor...............I would definately move.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:31 PM DST

[j-o-h-n in reply to j-o-h-n]

We would be up all night breaking each others balls.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:32 PM DST

[SPEEDYX in reply to j-o-h-n]

For sure I cant sleep anyway

[SPEEDYX in reply to j-o-h-n]

You wouldn't get off that easy..I follow you

[j-o-h-n in reply to SPEEDYX]

I would commit murder just to get away and into the joint.....(Pelican Bay no visitors)...

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 7:50 PM DST

[SPEEDYX in reply to j-o-h-n]

Not that easy .....Prison Reform....I will be there to greet you

[j-o-h-n in reply to SPEEDYX]

Haahahahahah ugotme.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 8:11 PM DST

[SPEEDYX in reply to j-o-h-n]

I defer to my older brother

[j-o-h-n in reply to SPEEDYX]

How old and is he good looking?

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 8:20 PM DST

[SPEEDYX in reply to j-o-h-n]

An ADONIS...Age plays no part

[j-o-h-n in reply to SPEEDYX]

A VENUS...Size matters

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 9:41 PM DST

[SPEEDYX in reply to j-o-h-n]

He was you I have no brother

[j-o-h-n in reply to SPEEDYX]

Doggonit, fooled me again........

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 10:09 PM DST

[SPEEDYX in reply to j-o-h-n]

A rarity

[j-o-h-n in reply to SPEEDYX]

I have a brother...... haven't spoken to him in years....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 10:20 PM DST

[SPEEDYX in reply to j-o-h-n]

I always wanted one...that's why I had for boys

[j-o-h-n in reply to SPEEDYX]

That's a gift from God..... you're lucky... do they get along with each other?

The tennis pros probably are competitive.

The one in college is away.

And the fourth one sells drugs LOL

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 10:26 PM DST

[SPEEDYX in reply to j-o-h-n]

All pretty tight...college one home remote online farmingdale...2nd one just get married lives close by and works with college guy part time they do power washing....oldest runs tennis club and other 2 help out on occassion..before covid we all meet for dinner guys night out on fridays ...special times

[j-o-h-n in reply to SPEEDYX]

That's a blessing..........

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 10:52 PM DST

[SPEEDYX in reply to j-o-h-n]

It truly is....and my father lived across the street..he enjoyed them so much they were there almost everyday just pass away last year...I see him everyday too worked together 40 years

[j-o-h-n in reply to SPEEDYX]

Last year.....so fresh in your mind..... Both your boys and your father were lucky. You working together for 40 years. When did you start at the age of 3?

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 11:08 PM DST

[SPEEDYX in reply to j-o-h-n]

Close 14....started business I went to school split sessions than to work to help ...my mom drove me

[j-o-h-n in reply to SPEEDYX]

Nice hard working kid..... good foundation.....

Were you parents born here in the US (I know originally from Crooklyn)?...

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 11:20 PM DST

[SPEEDYX in reply to j-o-h-n]

Yes both ...of course grandparents from Italy...immigrated here around 1920

[j-o-h-n in reply to SPEEDYX]

Did you ever find your grandparents coming over here? remember I'm the ellis island expert.....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 11:28 PM DST

[SPEEDYX in reply to j-o-h-n]

That's right thought of it when I wrote it...never checked it out...they didnt talk much about that experience...can you investigate

[j-o-h-n in reply to SPEEDYX]

Sure.... it would be a pleasure.... since I enjoy it.... like detective work. So in a private message send me their surnames, first names and any info you can furnish me with. If you know their age or year when they arrived and etc. sometimes that's helpful. If they have common surnames it becomes more difficult. If it works out I can do the same for your wife's family if she wishes... I need some time to do the research and I may have to get back to you for more info. Anyway, I'll give it a shot.........

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 11:42 PM DST

[SPEEDYX in reply to j-o-h-n]

Will do...I work on getting info and message you....good night long lost brother

[j-o-h-n in reply to SPEEDYX]

ciao

Good Luck. Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 11:52 PM DST

[j-o-h-n in reply to SPEEDYX]

Time for mangiare..... take care......

Bread and water....

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 8:21 PM DST

[j-o-h-n in reply to SPEEDYX]

Ruth Bader Ginsburg died (flash)

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 09/18/2020 8:14 PM DST

[Hidden in reply to j-o-h-n]

😫sad day for the court !

[j-o-h-n in reply to Hidden]

I think you mean bocce....

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 09/20/2020 3:18 PM DST

[Hidden in reply to j-o-h-n]

I love bocci

[j-o-h-n in reply to Hidden]

So does the mob.............

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 09/20/2020 5:39 PM DST

[SPEEDYX in reply to j-o-h-n]

So true ...I have a bocci court in my back yard...always a mob there to play.

[j-o-h-n in reply to SPEEDYX]

There's a big difference between A mob and The mob.....

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 5:42 PM DST

[SPEEDYX in reply to j-o-h-n]

Yes...It was a peaceful Mob

[j-o-h-n in reply to SPEEDYX]

Lou Campi....

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 6:08 PM DST

[SPEEDYX in reply to j-o-h-n]

Dick Weber only he didnt play bocci

[j-o-h-n in reply to SPEEDYX]

And he wore a glove.........

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 6:43 PM DST

[SPEEDYX in reply to j-o-h-n]

Black glove another Mob reference

[j-o-h-n in reply to SPEEDYX]

Black hand...... M others A nd F athers I talian A ssociation...

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 7:02 PM DST

[SPEEDYX in reply to j-o-h-n]

It is just a friendly group interested protecting and promoting...family....meeting to have big family dinners and playing bocci

[j-o-h-n in reply to SPEEDYX]

I agree.....but never let one of the guys in the family kiss you on the lips and call you Fredo......

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 7:28 PM DST

[SPEEDYX in reply to j-o-h-n]

Yea I stay away from Andrew Cuomo

[j-o-h-n in reply to SPEEDYX]

His Brother Chris.........

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 09/21/2020 7:40 PM DST

[SPEEDYX in reply to j-o-h-n]

You right...I stay away from him too...one in the same

[RalphieJr64]

Wow!

[Hidden]

Hey guy! How are you today ? Hang in there .💪