Recent data are showing that the covid-19 death rate among Italian men is much higher than among women: 80% of all deaths were in men, only 20% in women.
This pattern held true even in South Korea, where although the incidence was higher in women, men were more likely to die of it.
Also, I should add that testosterone has been found to be immunosuppressive against influenza,
It is well-established that ADT has an immune protective function:
Interestingly, normal levels of estrogen seem to be immunoprotective, but high levels, as in pregnant women or men on Bipolar Androgen Therapy (BAT), reverses the protection.
The implications are:
• If you are on continuous ADT, stay on it. This is true even if ADT has been augmented with Zytiga and prednisone, or anti-androgens.
• If you are on intermittent ADT, this might be a good time to end your ADT vacation.
• Men using Bipolar Androgen Therapy on a clinical trial should discuss the timing with the trial investigator. Anyone taking supraphysiologic doses of testosterone should consider this as well.
• If you are taking adjuvant ADT with radiation, consider sticking with it a little longer.