After two doses of KEYTRUDA immunotherapy; one infusion every 3 weeks. My PSA went from 86 to 1 over 6 weeks and I feel much better. Happy to be no longer hammering my immune system with chemo and instead working with it.
I have been stage 4 for almost 4-years and pretty much done most everything available and was about to explore LU-177, when this lined up.
I did a Foundation Medicine Liquid test (blood test) and they found my PC was considered ‘Microsatellite Instability High’ or MSI-H. This is not typically a good thing as it makes other treatments often less effective, but it opens the door for KEYTRUDA.
Feels like the fog has lifted and putting the dragon back in the cave.
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Chugach
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Also on Keytruda #47 infusion s over past 4 yrs..I was MSS., Had none of the required tumor markers for it to be effective, but I am HBM...high Burden Mutation (Hypermutated), Foundation Medicine identified checkpoint inhibitors as my treatment and currently in Complete Clinical Remission.
4 years is amazing. My husband was to have his 9th infusion this week, but got hit by a probable adrenal crisis. We are awaiting test results, so Keytruda is on hold.
Adrenal insufficiency is one of my side effects of long term use of Keytruda and 5 mg Prednisone combo, ..wear a medic alert bracelet for identification.
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Update in first Keytruda infusion
Anybody try Keytruda for APC 
Keytruda and brain tumors
