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Advanced Prostate Cancer

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Looking for Citations on research around low testosterone and low thyroid related to PCa, and about TRT for PCa.

yamobedeh profile image
4 Replies

I am about 27 months post RT, brachytherapy and 14 months post triple blockade ADT. Still on Avodart. Dx was ogliomet, G 8. Currently, scans are clear and PSA has increased slightly from <.008, to .011 over the last 6 months. Testosterone and thyroid are currently just below the lower limits, and have been for some time, as are WBC and RBC. Still have some residual fatigue and minor cognitive issues. I would appreciate any citations for research on replacement therapy for both these hormones in my situation, and on possible high dose testosterone in the future, if PSA rises above .2.

Many Thanks.

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yamobedeh
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pjoshea13 profile image
pjoshea13

You might find that fixing your thyroid issue will improve your testosterone [T] level. Nalakrats might respond here, but during his last ADT vacation, T bounced back to a much higher level than the pre-ADT high.

-Patrick

yamobedeh profile image
yamobedeh in reply to pjoshea13

Thanks. I'd wondered about that, too. My pre treatment testosterone and thyroid were not much higher than my current levels.

Tall_Allen profile image
Tall_Allen

Your PSA is very low. If it continues to be low for a while, you can discuss TRT. But I think you want to be sure you are completely cured before you take testosterone.

yamobedeh profile image
yamobedeh in reply to Tall_Allen

Thanks. I'm thinking that thyroid replacement might trigger a natural increase in T. Are you aware of any concerns around that?

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