I'm Wil. 66 y.o Black male. I was diagnosed with prostate cancer in 2008. Needless to say my life has been changed. My oncologist prescribed Lupron. Since 2008 it has kept my PSA reasonably low. Earlier this year my numbers were rising in spite of the Lupron. Next we tried Xtandi. All I can say is "brain fog". She now wants to start Zytiga with prednisone. Last week the results of a body scan showed metastatic lesions on 4 of my ribs. I am also scheduled for a hip replacement in 24 hours. For the last four years I have held up through all of the changes. Now I am afraid. Reading the posts over the last 4 months I have been uplifted by the caring and support you have shown to one another. Any suggestions?
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cuba2019
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Talk to your oncologist about docetaxel before you try Zytiga (Zytiga sometimes works for a longer time when you do it in that order). Also, discuss Xofigo. Possibly, pair docetaxel or Xofigo with Provenge.
How's your bone mineral density? Are you taking Zometa or Xgeva? If so, consider pairing with Celebrex.
I just received my latest PSA. It is .54. Is it possible that the lesions have been there for a while? Would they continue to grow or multiply with even with low PSA's? Thanks so much for your help.
My PSA is undetectable yet lesions still show up on scans, however these are deemed “sclerotic” lesions or scars left behind from when cancer was active. Does your scan report say these lesions are active metastasis?
You have done well my friend to kept the beast at bay for so long. My oncologist and I both believe this disease is easier to manage when it’s small. Find and aggressive oncologist and get on it fast!
I've had a similar experience, though nothing like a hip replacement. (In fact, I'd be a dubious choice for that since I'm on Eliquis and bleeding is an issue.) What I've found over the five years since my first diagnosis is that this version of our cancer is very clever. A treatment will work for a while, psa goes down, and outlook is good, and then the numbers start climbing and new mets are discovered. For instance, with Lupron (which restricts the production of testosterone) the mCRPC starts producing its own, which causes the rise and spread. Likewise for other treatments. All the oncologists can do, at this point (and given that this cancer is incurable) is buy us time and sometimes that time is not pleasant. I finished a round of chemo about a month ago--no fun, though the results were good. And the recovery time, once the chemo passed, presented a number of unenjoyable issues.
Attitude is everything, Wil. It's too easy to think of all the difficulties and pain that goes with this disease and forget that there are so many things that make life still good. I have one infallible remedy for those times when you get depressed. Works every time and no pills involved. It's this:
Do something nice for someone else.
It's always worked for me and I know it will for you. Fight the good fight, Wil. We're all with you.
Greetings Cubano.... What's your age? Location? treatment center? Doctor's name(s)? All info is voluntary but it helps us help you and helps us too. If do respond please do so in a future date and not directly to me. Thank you...
It sounds like you've done a great job--2008! Really amazing success I'd say. Good luck tomorrow on your hip and keep going, just one day at a time. Best to you and thinking good positive thoughts.
Cuba- I am not as knowledgeable as others on the site, so I will leave the recommendations to them. But- just wanted you to know that I had a total knee replacement 4 years into my treatment for PC , back surgery a year later, and a follow up procedure on my knee this past December. The PC was unaffected by all 3 and is still responding to Lupron. All the best with your new hip.
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