April 2016 Robotic Surgery, June 2017 Casodex/Lurpon, October 2017 Proton Radiation, January 2018 Chemo (4X). I continued Lupron from June 17 through January 2019. Stopped Lupron due to side effects January 20 this year. Currently no treatment, Q30 Day ultra-sensisitve PSA & T level - PSA undetectable, T Level 12 in February & 14 in March. QUESTION: Both oncologist and urologist suggest considering Testosterone therapy. Any feedback appreciated!
Testosterone Therapy After Lupron? - Advanced Prostate...
Alternating Lupron and Testosterone (called Bipolar Androgen Therapy - BAT) seemed to be effective in some small (29 patients) trials in men who were still hormone sensitive and had undetectable or minimal metastases. They alternated 3 months of each. Here's what they learned so far:
As might be expected from some of my posts, I would opt for testosterone replacement therapt [TRT].
You should expect PSA to rise as T is restored, so don't be concerned by the first reading. You need to relax & wait for the trend. Hopefully, you will have a longiss PSA doubling time [PSADT], e.g. >18 months, or much longer.
Here is Dr Myers on the subject of TRT & PCa:
You are in a very good place. I am a fan of BAT but I think it is way overkill in your case with PSA undetectable and still sensitive to casodex and lupron. If your docs recommend T for QOL, go for it! I think testosterone replacement therapy and if so, aim to get a fairly high T level but within the normal range. (not supra T at this stage) PCa loves low-normal T. If PSA starts rising too fast lupron and/or casodex should knock it back, then stop them, see what it does. There is a good chance you will be able to cycle PSA from very low to low and back and get maximum bang from lupron and casodex.