Israeli Technology strikes again! Most radiation delivered today emit Beta radiation, which has a tendency to harm normal tissue. Alpha radiation is so powerful, that it will break both strands on a cancer cells DNA, and not harm the surrounding healthy tissue. The Isotope is not Radium 223, but Radium 224. There have been 12 Peer Reviewed Papers--->the intellectuals here can search them.
The new company in Israel raised 30 million dollars. It is called Alpha Tau. Alpha Radiation is unique when compared to other types of Brachytherapy, where sealed radiation seeds or micro capsules are placed inside or next to the tumor emitting Beta or Gamma Radiation.
But these typical Radiations only causes a single break in the DNA of the Cancer Cell, which allows some cells to recover over time. Also it is not as focused and causes local destruction of healthy tissue. The Israeli Researchers believe that what they now call DaRT Technology, has great value not only in destroying active tumors, but in preventing cancer from spreading to other areas in the body.
DaRT----> stands for [Diffusing Alpha-Emitters Radiation Therapy]. Human trials in Israel and Italy for Squamous Cell Carcinoma, as well as other cancers in New York and Montreal, are getting ready. New trials planned in 2019 will take place in France, and again in New York---> specific for Pancreatic and Prostate Cancer. [I assume Memorial Sloan Kettering], is participating. Also Russia is picking it up for Breast Cancer, and Israel again for Prostate Cancer.
The researchers claim they can treat any solid Tumor or Metastasis. In the Squamous C.C. study they eliminated 70% of the tumors completely, and in 100% they saw shrinkage.
The company has designed treatment kits, that can be shipped to any Hospital, anywhere. Patients can be treated in an Outpatient Clinic, without radiation shielding. The half life of the Radium 224 is about 6.5 days. And is all gone in 2 weeks. No radioactivity will be left because of the fast half life. The Kit must arrive over night. No one can be late. The typical Breast Cancer Patient may need 12 Needle Applicators, each containing 6 DaRT Seeds. Timing has to be perfect. To meet this critical time frame, Alpha Tau will need to build production facilities around the world. There is one in Israel, and one being Built right now in Massachusetts, another being scheduled for Japan, and one inside Western Europe.
Alpha Tau expects European Approval in 2020. The USA in 2022, but hopes with the FDA new fast rack program, that it can be approved also in 2020. The Researchers are all thrilled as they are curing patients in the Trials, and saving lives. Patients with an Overall Survival of Weeks, were Cancer Free in 60 days.
One question I have, as to Pca---> if the Prostate was removed, and a patient developed metastasis or had them from the beginning, can this technique, go after individual well defined Metastasis? The Researchers claim that when the DaRT Technology is used that the Immune System, then recognizes and is stimulated to attack the same tumors elsewhere in the body. The information I have so far does not explain how that is done. If true then my question about metastasis would be answered. Anyway great work by the Jewish People.