I'm interested in opinions regarding late edition of Zytiga to ADT treatment. I was diagnosed state IV, Gleason 9, 4 bones metastases with PSA of 11.2. I was started on ADT and so far doing well.....PSA is fluctuating between .01 to .06 over 18 months, I started treatment 5/2017) During that time in my research I began to notice that the standard of care at this point that with my current assessment that Zytiga/Prednisone is given with ADT at diagnosis for longer remission. However, I was started only on ADT (Lupron/Zometa/Biculatimide). My question is: Is it too late to start Zytiga with ADT to extend remission? Much of the reports I have read indicate that it should be started when ADT is started. So was wondering if its too late to get an efficacious remission. Thanks for any comments or suggestions or opinions.