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Advanced Prostate Cancer
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Most Effective Anti-Depressant

Hello All You Brave WARRIORS...

I was curious if you could let me know which anti-depressant is the best while on Zytiga, Lupron and Jevtana.

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Ask if your medical center has a Quality of Life center....there you can usually meet with counselors who specialize in cancer patients and also consult with a Doc or Nurse Practitioner who specialize in meds for depression and even fatigue.

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I think nobody knows. May be the antidepressants which are activating, Wellbutrin, Cymbalta and Effexor could be useful.

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I swear I remember someone here saying there was an antidepressant that had an off label effect on prostate cancer.

If so, that would be a good one to start with.

Also, a vigorous exercise regime is supposed to be highly effective, alone or in conjunction with medication.

Maybe try a serious investment into a personal trainer and an intense 5 day a week training regime, for 8 weeks. See what that does.

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We are all different so different durgs work differenly on people. Trial and error. I am now on effexor and abilify. The combination is good for mood but i have troble sleeping though.

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I would agree with (cesanon) and I would go further by saying Anti-depressants are not the way I dealt with Hormone treatments (as it is one more drug). I did not deal with being too depressed, but more lethargic due to the hormones. Exercise and working out are BEST TRUE way to combat depression. 5 days a week work on keeping what muscle and flexibility you have and try to gain some back! Start by getting outside and get 15 to 20 mins of sun every day, start taking D3 with K2, and a great B-Complex are great starters. and then take a trusted and tested curcumin/turmeric supplement. I could write a book on what I have learned in the last 3 years, and I wish I knew the many ways to address prostate cancer 3 years ago. Lastly, Read the book (How Not to Die) by Dr. Gregor. It will open your mind!

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In lieu of a team that is familiar with oncology try to find a good psychiatrist to oversee that med in conversation with your oncologist. Psychotropics are highly individualized.

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I was put on Effexer (Venlafaxine) to help with hot flashes. It is a anti depressent but is used off label for hot flashes. May help with both!

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Hello, ZOLOFT HAS BEEN REALLY GOOD FOR ME.. BEEN ON IT FOR ABOUT A MONTH.. TAKES ABOUT 2 WEEKS TO BUILD UP AND TAKE EFFCT.. TAKE 1/2 PILL OR 50 MG DAILY.

I AM ON ZYTIGA AND PREDNISONE.

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Your doctor may have you try clomipramine (Anafranil), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or another antidepressant, depending on your age, health, and symptoms. It can take a couple of months for drugs to start to work. Make sure you consult with a psychiatrist as they are the most familiar with the psychopharmacology. It often takes 40 to 60 mg of a particular drug daily to have any effect at all and family practioners, oncologists, and urologists are often poorly informed or prepared to help.

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i use herbal supplements:

holy basil 450mg capsule, one in morning, one before bed.

Used to use St. John's wort but it began spiking my blood pressure.

ginkgo biloba, 2-3 times/day. great stuff!

take a walk in the sun everyday, or Vit. D3, 1-5 grams/day

stop ALL processed foods! they're all loaded with various toxic crap. eat food you recognize - mostly fruits and veggies, raw and lightly cooked is best.

fish poultry and dairy for protein, but should only be 1/3 of your daily total food intake.

if you're a bit overweight and can live without white rice, white potatoes, bread and pasta, you can drop up to 50 lbs in about 3-4 months.

good luck.

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My doctor has me on Effexor twice a day,wife says it’s working pretty good. Fight the good Fight

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I was not on any anti-depressants during my lupron injections (one year). Not using it any longer. Got gynemastia. Don't know if that will subside now that I am not on lupron (and off casedex as well). Have stage four NSCLC not related to PC so focus is off prostate and on lung cancer as it will kill me before prostate cancer will. Looking forward to starting clinical trial for keytruda this week. Good lock and god speed to all of us on these cancer sites!

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Different psychotropic meds work differently on everyone. There are multiple classes of meds- SSRI’s, MAO’s, etc and within each class multiple meds. There IS a relatively new test that involves a cheek swab that provides results in a few weeks with what medications are most likely to be effective with you specifically. It’s new enough that few psychiatrists are using but my PCP was familiar with it.

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The generic for Effexor is venlafaxine. I am on Eligard (previously on Lupron for 4 years) and venlafaxine stops 95% of the sweats and hot flashes. It starts working the same day you take it. Only issue is that you must come off of it very carefully if you ever stop taking it...which I have no plans to do...I will be on Eligard the rest of my life.

Live strong!

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The best antidepressant is a loving supportive partner. Second best is a good exercise routine. I have a naturally upbeat nature so it hasn't been problem for me but try the natural stuff before drugs.

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