Okay everyone just thought I'd throw this question out and see if anyone has had anything similar happening to them. My husband has prostate cancer with mets to his bones. Oncologist started him on Cabazitaxel chemo on June 7th and his PSA before 1st treatment was 657 on May 30th and then afterwards it was 683 on June 26th and then he had his 2nd treatment and bloodwork in A.M. before 3rd treatment was PSA 981 on July 19th. His Alkaline Phosphate level on June 7th the day of first treatment was 211 but now on July 19th it was down to 163 which is still high but lowered from when he first started. Just wondering if anyone out there has had any results like this. Just very worried about the rising PSA despite chemo treatments.