I AM NEW HERE. BEEN DEALING WITH PROSTATE CANCER FOR 3 YEARS. PSA WENT FROM 4 TO 19. SPREAD TO LYMPH NODES AND BONES. HAD 45 DAYS OF RADIATION,VARIOUS PILLS THEN 7 TREATMENTS OF CHEMO AND HORMONE TREATMENTS . NOTHING IS WORKING AND PSA NOW 175. HAVING BIOPSY THIS WEEK TO DETERMINE IF THERE ARE ANY DRUGS THAT WOULD WORK.
INTERESTED IN FINDING RESULTS IN GERMANY WITH LU 177 AND WHO TO CONTACT.
First you have to make sure your cancer is PSMA-avid using a PSMA Pet scan
At the University of Heidelberg, contact Uwe Haberkorn
Phone: 06221 56-7731
What is PSMA avid please?
It isn't really a trial of Lu 177 you are interested in. Lu -177 is just a beta-emitter that kills cells. It's what the Lu-177 attaches TO that is important. I think you are talking about Lu-177-PSMA-617. PSMA-617 is a "ligand" that seeks out and attaches to the PSMA protein in prostate cancer cells. After it is attached, the radioactive part can kill the cancer cell. Not every kind of prostate cancer expresses PSMA. For example, neuroendocrine PC does not, nor does PC that has progressed beyond a certain point. For that reason, they have to first check whether your particular type of PC expresses PSMA in sufficient amounts to make treatment with Lu-177-PSMA-617 worthwhile (called "PSMA - avid"). They use a PSMA PET scan for this purpose (either Ga-68-PSMA-11, DCFPyL, or similar)
Thanks Allen Got it.
I am also interested in Lu-177.
I had Gleason 9 2012. Prostate removed, imrt, then 2 years of Lupron. After ND PSA for 5 years. May 2018 psa jumped to .8.
Bone scan revealed spots on Pelvic area that weren’t there in 2012. Some spots on my chest, but they were there in 2012. I had them checked (no cancer).
But the spots on my pelvic area area are the big problem. Last week I started Lupron and bacultmate. Next month they want me to take Zytega.
Question, Can you get treated with Lu-177 while on Lupron? Someone just told me about Lu-177 and it sounds like a good thing.
Thanks Tall_Allen for your nice post.
Yes, they would expect you to stay on Lupron. But why not see what the hormone therapy does first?
Yes I am going to find out if the Lupron works first but I don’t want to on Lupron for the rest of my life I am only 60.
There is no therapy that replaces Lupron - they are all "in addition to." Intermittent ADT will give you vacations.