Implications of PSMA directed therapy

[snoraste]

In case you missed

practiceupdate.com/c/64223/...

[andrew61]

I’m staring Lu177-PSMA at UCLA in a couple of weeks.

[wrando in reply to andrew61]

Have you been tested for PSMA yet?

[Hawkwoman76 in reply to andrew61]

Is this part of a clinical trial & did it start a while ago? My husband just got his 2nd treatment of taxotere & really only has chemo & radium 233 in his arsenal of prostate cancer fighting drugs. I’ve been trying to see if he might be a candidate for Lu177-PSMA. Just from my early investigation into this drug I see that you can go to Germany & Australia & maybe a couple of other countries for treatment, but was really interested in some place in US. We live in San Diego. Thx for any info you might be able to tell me. Hawkwoman76

[andrew61 in reply to Hawkwoman76]

It is a phase 2 trial. You get randomized between 2 pretty close doses of radiation. Two doctors came out from Germany to help setup the program. The treatment is supposed to be the same as in Germany (although there are several clinics doing it in Germany so there’s probably some variations from clinic to clinic).

UCLA will stop enrolling new patients once the global phase 3 trial starts. In the phase 3 trial individuals will be randomized to treatment or a placebo.

[snoraste in reply to Hawkwoman76]

I don’t know if phase 2 is still recruiting, but I’d give it a try. In phase 3 you are randomized and may not get it

[andrew61]

Yes, PSMA and Choline scans both show PCa in numerous lymph nodes.