This is my first post, we live in UK and my husband Steve was diagnosed with aggressive prostate cancer in 2011 with lymph node involvement. PSA 14, Gleason 10,
Started 3 monthly zoladex injections straight away which he still has and also 40 radiotherapy treatments which kept his PSA to around 0.6 for 4 years.
He then started Casodex but it did not work so he was prescribed Enzalutamide, this worked well for almost 2 years but then PSA started to climb and scans revealed bone mets and he had 5 Radium 223 treatments. Further scans showed spots in the abdomen.
Last October he started chemo (Docetaxel) but PSA continued to rise and after 4 cycles oncologist said it was not working and changed to Cabazitaxel. PSA dropped after the first few cycles but then began to rise after cycle 4 and 5, PSA currently 20.
The oncologist is very negative and implies that there are very few options remaining, he has not had Aberiterone but onc says this rarely works after enzalutamide fails because thay work in a similar way. Has anyone experienced this?
Any advice or suggestions would be so appreciated as I am very worried that we are running out of treatment options
Sometimes Zytiga will work again if it is tried after Jevtana. He can try estrogen patches too. If you can afford to go to Germany for treatment, they have had some good success with some radiopharmaceuticals (eg Lu-177-PSMA).
Thank you so much, will look into this, any idea of a good cancer centre in Germany?
There are several in Germany, and I think that the top centers cooperate on nuclear medicine, but the one that seems to have the most experience is Uwe Haberkorn at the University of Heidelberg. Contact details on the following: