My husband has been Lupron, casodex and finished upfront Docetaxel( 6 cycles finished in October). DX metastatic 2/1/2017 with PSA of 1044 at 47 yrs old. His PSA has steadily dropped to 2.4 as of 6 weeks ago. This week he’s experiencing pain in his back and ribs. Is this pain a probable sign of progression despite a responding PSA? What are experiences with pain vs PSA response? He also fell off the bed hard onto his side about 10 days ago I’m hopeful it might have something to do with it?