When I first went on to rivaroxaban, a year ago, I got terrific indigestion, although I'm still not sure whether it was indigestion or clot pains. However, it stopped once I went on to the maintenance dose after 3 weeks, and I thought no more about it.
But yesterday, I forgot to take my pill at breakfast (don't know why - this NEVER happens!) and then forgot to take it at lunch. So I decided to take it about 2 hours after lunch, on the grounds that my stomach should still be fairly full. Big mistake - I had indigestion all the rest of the day! So if you do need to take your rivaroxaban at an unusual hour - EAT SOMETHING, even if it's only a piece of fruit!