Hi, have posted before but wanted a bit of reassurance please. Following a DVT in thigh in December, which GP believes was from starting HRT 10 months earlier, I have been on apixiban 5mg twice a day for 6 months. Following a review on Monday consultant reduced this to 2.5mg twice a day for a while. Has anyone else reduced their dose, if so did you feel any different, were you concerned you were not covered. Today at work I sort of panicked and convinced myself my chest was heavy and my arms were numb, all anxiety I expect as nothing came of it. I also suffer with IBS and have been having gastritis type burning pains for last few months which I think may be the tablet, especially as within 2 days this seems more bearable. Any thoughts greatly appreciated.