The BMJ Learning module "Maintaing Patients on Anticoagulants" highlights an interaction between oral Omeprazole (to treat acid reflux) and warfarin and suggests that coadministration with warfarin should be avoided or closely monitored. I had been prescribe Omeprazole but had severe stomach pains and stopped taking it after just one day and informed my GP who then prescribe Lansoprazole. Whilst this didn't cause any side effects it did elevate my INR but was quickly identified as I self-test weekly and in this case after 3 days. I also self-dose so I could reduce my warfarin and monitor it again in 3 days to ensure that I'm back within my therapeutic range.
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